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Air Quality Guidelines Global Update 2005 - World Health ...

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10. Particulate matter<br />

Jonathan M. Samet, Michael Brauer, Richard Schlesinger<br />

Introduction<br />

Since the second edition of <strong>Air</strong> quality guidelines for Europe was issued in 2000<br />

(1), there has been an explosive growth in research relevant to the health effects<br />

of airborne PM. The evidence comes from a variety of research disciplines, including<br />

epidemiology, toxicology, exposure assessment and atmospheric sciences.<br />

The evidence obtained has deepened understanding of the risks posed to<br />

human health and to ecosystems by airborne particles, and also provided insights<br />

into the complexity of airborne particles and their myriad sources, along with the<br />

attendant implications for control. The scientific foundation for proposing air<br />

quality guidelines is far more substantial than in the past; the voluminous scope<br />

of available evidence, however, poses a challenge in developing guidelines, as the<br />

amount of evidence for a number of adverse health effects is now increasingly<br />

sufficient for this purpose but not easily summarized, either quantitatively or<br />

qualitatively. For some of the health outcomes, including increased risk of mortality<br />

on a short-term basis, dose–response relationships have been demonstrated<br />

at concentrations extending, at the lowest levels, well into the ranges measured at<br />

present in many cities in both developed and developing countries. The consequent<br />

inability to identify levels below which adverse effects are not anticipated<br />

implies that any standard may leave some residual risk unless concentrations are<br />

reduced to background levels.<br />

A systematic review of this new evidence is beyond the scope of this chapter,<br />

which draws extensively from recent comprehensive syntheses and from the<br />

meta-analyses of time series studies carried out by Anderson et al. for WHO (2).<br />

The full suite of evidence on PM was assembled by the US Environmental Protection<br />

Agency (USEPA) in its 2004 document <strong>Air</strong> quality criteria for particulate<br />

matter (3). The related document, Review of the national ambient air quality<br />

standards for particulate matter: policy assessment of scientific and technical<br />

information (4), provides a distillation of the findings of the criteria document<br />

and policy implications. In 1998, the US National Research Council established<br />

its Committee on Research Priorities for <strong>Air</strong>borne Particulate Matter, which was<br />

charged with setting out an agenda for PM research and then tracking progress<br />

on this agenda (5). In its fourth and final report, the Committee gauged progress<br />

on its research agenda, based on a process involving expert judgement and a systematic<br />

review. It also highlighted uncertainties in the evidence available on PM,<br />

across its framework that begins with sources of PM and ends with adverse effects<br />

217

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