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Air Quality Guidelines Global Update 2005 - World Health ...

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HUMAN EXPOSURE TO AIR POLLUTION<br />

both exposures from outdoor origin and indoor sources) or only in that part of<br />

the exposure that is from outdoor origin. For pollutants such as benzene (where<br />

no constituent differences exist and the toxicity of outdoor and indoor exposure<br />

is the same) optimal exposure-based air quality management would in some cities<br />

point to ambient sources and in others to indoor sources (even consumer<br />

products), depending on which sources dominate the personal exposure (4). For<br />

PM, however, the composition of particles of outdoor origin can be very different<br />

from that of particles from indoor sources. Methodological investigations<br />

have therefore pointed out that ambient and non-ambient exposures need to be<br />

considered as two separate classes of pollutant (36,37). Ebelt and colleagues (38)<br />

developed separate estimates of exposure to ambient and non-ambient particles<br />

based on time–activity data and the use of particle sulfate measurements as a<br />

tracer for indoor infiltration of ambient particles, and evaluated their relative effect<br />

on cardiopulmonary health. Although total and non-ambient particle exposures<br />

were not associated with any of the health outcomes, ambient exposures<br />

were associated with reduced lung function, lower systolic blood pressure, increased<br />

heart rate and increased supraventricular ectopic heartbeats. These results<br />

obviously do not imply that non-ambient exposures cannot have health effects<br />

of their own in other settings.<br />

Since people spend most of their time indoors, most of the exposure to pollution<br />

of outdoor origin takes place indoors, where exposure can be modified by<br />

the building and its equipment (e.g. air conditioning). If one is primarily interested<br />

in pollutants of outdoor origin, indoor concentrations are of interest only<br />

in so far as they reflect or do not reflect outdoor concentrations and sources. This<br />

concept has been most advanced for particle exposure, but can apply to other<br />

components with significant indoor sources as well, provided that it is not the<br />

pollutant per se that is causing the health effects. From a policy perspective, however,<br />

interventions based on reducing specific indicator pollutants that are not<br />

necessarily directly related to health may not result in the most effective strategies.<br />

For example, it remains unclear whether the observed association between<br />

nitrogen dioxide and health is due to the nitrogen dioxide itself or whether nitrogen<br />

dioxide is an indicator of other correlated pollutants, such as ultrafine particles<br />

and traffic-related pollution in general (3).<br />

Reduction of pollution generated indoors<br />

One of the most practical ways of reducing exposure to indoor sources of air pollution<br />

has been the outdoor dissemination of indoor sources of pollution. For example,<br />

while chimneys do not change the quantity of smoke emitted, they reduce<br />

indoor exposures to smoke substantially.<br />

Indoor sources can make a substantial contribution to outdoor concentrations<br />

in places where there are large, widespread sources of indoor air pollution. For example,<br />

the infamous London Fog was caused essentially by indoor use of coal for<br />

75

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