Black Cohosh - Non-Timber Forest Products
Black Cohosh - Non-Timber Forest Products
Black Cohosh - Non-Timber Forest Products
You also want an ePaper? Increase the reach of your titles
YUMPU automatically turns print PDFs into web optimized ePapers that Google loves.
Liske, E.; Boblitz, N.; Henneicke-von Zepelin, H.H. 2000. Therapy of<br />
climacteric complaints with Cimicifuga racemosa; data on effect and<br />
efficacy from a randomized controlled double-blind study. In: Rietbrock,<br />
N.; Donath, M.F.; Loew, D. [and others], (eds.). Phytopharmaka VI.<br />
Darmstadt: Steinkopff:. p. 247-257. In German.<br />
Describes a study on the effectiveness of black cohosh for treating<br />
climacteric complaints.<br />
Keywords: Clinical studies, medicinal uses.<br />
Liske, E.; Wüstenberg, P. 1998. Therapy of climacteric complaints with<br />
Cimicifuga racemosa: herbal medicine with clinically proven evidence.<br />
Menopause. 5(4): 250.<br />
Compares the effects of two different dosages of Remifemin ® (40 mg vs.<br />
127 mg isopropanolic black cohosh extract) in a double-blind randomized<br />
6-month clinical study of 152 female patients with climacteric complaints.<br />
The two dosages showed similar efficacy and safety. Levels of luteinizing<br />
hormone, follicle stimulating hormone, sex hormone binding globulin,<br />
prolactin and estradiol, and vaginal cytology were unaffected. The authors<br />
concluded that the product did not have an estrogen-like (hormone) effect.<br />
Keywords: Clinical studies, dosage, Remifemin ® .<br />
Liske, E.; Wüstenberg, P.; Boblitz, N. 1998. Human-pharmacological<br />
investigations during treatment of climacteric complaints with Cimicifuga<br />
racemosa (Remifemin ® ): no estrogen-like effects. ESCOP, The European<br />
Phytojournal. http://www.ex.ac.uk/phytonet/phytojournal/poster71.pdf.<br />
[Date accessed: September 13, 2004].<br />
Previous research has suggested estrogen-like effects for black cohosh,<br />
though recent findings have questioned this claim. This study, involving 152<br />
patients, showed that the commercial preparation Remifemin ® had no effect<br />
on concentrations of luteinizing hormone, follicle stimulating hormone,<br />
sex hormone-binding globulin, prolactin, or estradiol. The proliferation<br />
of vaginal mucosa did not change in an estrogenic manner; however, the<br />
Kupperman Menopausal Index indicated a significant improvement in<br />
climacteric symptoms. The authors found black cohosh a safe and effective<br />
alternative to hormone replacement therapy.<br />
Keywords: Assessment scales, clinical studies, physiological actions,<br />
Remifemin ® .<br />
52
Change language