Black Cohosh - Non-Timber Forest Products

Nisslein, T.; Freudenstein, J. 2003. Effects of an isopropanolic extract of
Cimicifuga racemosa on urinary crosslinks and other parameters of bone
quality in an ovariectomized rat model of osteoporosis. Journal of Bone
Mineral Metabolism. 21(6): 370-376.
Investigates the effects of black cohosh on bone loss associated with
decreased estrogen levels. Ovariectomized rats on diets containing black
cohosh showed significantly less bone loss starting 2 to 5 weeks after
treatment began through the completion of the study at 7 weeks.
Keywords: Clinical studies, medicinal uses, physiological actions.
Noguchi, M.; Naga, M.; Koeda, M. [and others]. 1998. Vasoactive effects
of cimicifugic acids C and D, and fukinolic acid in Cimicifuga rhizome.
Biological and Pharmaceutical Bulletin. 21(11): 1163-1168.
Examines the vasoactivity of several constituents of black cohosh.
Keywords: Chemical constituents, clinical studies.
Onorato, J.; Henion, J.D. 2001. Evaluation of triterpene glycoside
estrogenic activity using LC/MS and immunoaffinity extraction.
Analytical Chemistry. 73(19): 4704-4710.
Tests the estrogen-like activity of three triterpene glycosides present in the
rhizomes of black cohosh. One glycoside, 27–deoxyacetin aglycon, showed
weak binding (4 percent), whereas none of the other glycosides or their
metabolic products showed binding to estrogen receptor sites.
Keywords: Chemical constituents, clinical studies, physiological actions.
Papps, F.A. 2000. Therapeutic use and associated biochemistry of
Cimicifuga racemosa in the treatment of menopausal symptoms.
Australian Journal of Medical Herbalism. 12(1): 22-26.
Reviews research related to the use of black cohosh to treat symptoms of
menopause, with a focus on biochemical mechanisms and chemistry.
Keywords: Chemical constituents, medicinal uses, research reviews.
Pepping, J. 1999. Black cohosh: Cimicifuga racemosa. American Journal of
Health-System Pharmacy. 56(14): 1400-1402.
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