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Black Cohosh - Non-Timber Forest Products

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Evaluates constituents from black cohosh for anti-HIV activity. Actein, a<br />

tetracyclic triterpenoid, showed potent anti-HIV activity, and 12 saponins<br />

showed moderate anti-HIV activity.<br />

Keywords: Chemical constituents, clinical studies, medicinal uses.<br />

Schaper and Brummer, GmbH. 1997. Remifemin ® : a plant-based<br />

gynecological agent. Salzgitter, Germany: Schaper and Brummer GmbH.<br />

[Number of pages unknown].<br />

Summarizes a controlled, randomized, double-blind, multicenter clinical<br />

study involving 152 women before or after menopause (age 43 to 60 years)<br />

who were experiencing moderate neurovegetative climacteric complaints.<br />

Patients received either one or two 20-mg tablets twice daily for three<br />

months. Patients were examined before starting treatment, at 2, 4, and 8<br />

weeks of treatment, and after the study ended. Effectiveness was evaluated<br />

using the Kupperman Menopausal Index, the Self-Assessment Depression<br />

Scale, the Clinical Global Impression scale, and vaginal cytology indices.<br />

Levels of luteinizing hormone, follicle stimulating hormone, estradiol–17b,<br />

prolactin, and globulin were also measured. Both dosages showed similar<br />

effectiveness and safety results; the Kupperman Menopausal Index and Self-<br />

Assessment Depression Scale showed significantly decreased scores, but<br />

no changes were seen in vaginal cytology or hormone levels. No details are<br />

given on adverse effects, though the treatment was rated as well tolerated<br />

by 95 percent of patients and 92 percent of their doctors, and as “good”<br />

or “very good” in 80 percent of cases. This brochure is provided by the<br />

manufacturers of Remifemin ® .<br />

Keywords: Assessment scales, clinical studies, dosage, luteinizing hormone,<br />

medicinal uses, menopause, Remifemin ®<br />

Schlosser, K.K. 2002. Counting cohosh. North Carolina Wildflower<br />

Preservation Society. 14(2): [Number of pages unknown]. http://www.<br />

nps.gov/plants/medicinal/pubs/countingcohosh.htm. [Date accessed:<br />

September 13, 2004].<br />

Describes a monitoring study of black cohosh in the forests of North<br />

Carolina sponsored by the Plant Conservation Alliance - Medicinal Plant<br />

Working Group and the <strong>Forest</strong> Service, and executed by members of the<br />

Garden Club of America. In this study, black cohosh plants in designated 10<br />

X 10-meter plots were counted, measured, and evaluated for health status.<br />

Plots were divided into one of three groups: controls with no harvest, 33<br />

percent harvest, or 66 percent harvest. The purpose of the research is to<br />

66

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