Black Cohosh - Non-Timber Forest Products
Black Cohosh - Non-Timber Forest Products
Black Cohosh - Non-Timber Forest Products
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Muñoz, G.H.; Pluchino, S. 2003. Cimicifuga racemosa for the treatment<br />
of hot flushes in women surviving breast cancer. Maturitas. 44(Suppl. 1):<br />
S59-S65.<br />
Examines the use of black cohosh (extract CR BNO 1055, found in<br />
Klimadynon ® /Menofem ® ) to treat hot flashes for breast cancer survivors on<br />
tamoxifen. After masectomy, radiation, and chemotherapy, patients were<br />
divided into two groups: one group received tamoxifen and black cohosh,<br />
the other received tamoxifen only. After 12 months of treatment, the group<br />
receiving black cohosh and tamoxifen showed a significant reduction in the<br />
number and severity of hot flashes compared to the group receiving only<br />
tamoxifen.<br />
Keywords: Cancer, clinical studies, hot flashes, medicinal uses.<br />
Murray, M.T. 2003. <strong>Black</strong> cohosh – is there really a concern? http://www.<br />
doctormurray.com/newsletter/1-16-2003.htm. [Date accessed: September<br />
13, 2004].<br />
Responds to a study by Davis and others (2003) that found that mice<br />
bred to express breast cancer, when fed a diet with black cohosh, showed<br />
significantly higher rates of breast cancer cells metastasizing to the lungs.<br />
The author discusses several issues related to this study: (1) the research<br />
was conducted on mice and not on humans, and black cohosh may not have<br />
the same effects on two different organisms; (2) the mice used in the study<br />
were specifically bred to develop breast cancer, which may have skewed<br />
the results; and (3) previous research has shown that black cohosh has an<br />
inhibitory effect on cancer cells. Research on the safety of black cohosh by<br />
Dog and others (2003) is summarized.<br />
Keywords: Research reviews, toxicity.<br />
National Institutes of Health, National Toxicology Program. 1999.<br />
Summary of data for chemical selection: black cohosh. http://ntp.<br />
niehs.nih.gov/INDEX.CFM?OBJECTID=03DA9AE1-E585-C748-<br />
5328B384769DCD0F. [Date accessed: January 7, 2004].<br />
Summarizes data on the chemical constituents, mechanism of action,<br />
and safety of black cohosh. Includes information on human and animal<br />
exposure, manufacturers and distributors, usage, history, regulations, and<br />
biological effects.<br />
Keywords: Chemical constituents, medicinal uses, physiological actions,<br />
products, side effects, toxicity.<br />
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