ST 520 Statistical Principles of Clinical Trials - NCSU Statistics ...

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CHAPTER 10 ST 520, A. TSIATIS and D. Zhang Although an information-based monitoring strategy, such as that outlined in section 10.5.2, is not always practical, I believe that information (i.e. [se{ ˆ ∆(t)}] −2 ) should also be monitored as the study progresses and if this deviates substantially from that desired, then the study team should be made aware of this fact so that possible changes in design might be considered. The earlier in the study that problems are discovered, the easier they are to fix. PAGE 196
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TABLE OF CONTENTS ST 520, A. Tsiati
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CHAPTER 1 ST 520, A. TSIATIS and D.
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ST 520 Statistical Principles of Clinical Trials - NCSU Statistics ...

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