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Cancer Research in Switzerland - Krebsliga Schweiz

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Cl<strong>in</strong>ical research<br />

Challenges for cl<strong>in</strong>ical cancer research <strong>in</strong> <strong>Switzerland</strong><br />

The aim of patient-centred cl<strong>in</strong>ical cancer research is<br />

to develop new cancer therapies and to optimize<br />

exist<strong>in</strong>g tumour therapies so as to improve the prognosis<br />

and tolerability of treatment <strong>in</strong> patients with<br />

cancer. Typical research questions are, for example:<br />

Will a comb<strong>in</strong>ation of different chemotherapy drugs<br />

produce better results? Will this cause more side effects?<br />

What is the optimal comb<strong>in</strong>ation of the three<br />

types of treatment – chemotherapy, radiation therapy,<br />

and surgery – for certa<strong>in</strong> types of cancer and<br />

patient groups? As chemotherapy is often very expensive,<br />

an <strong>in</strong>creas<strong>in</strong>g number of <strong>in</strong>vestigations are<br />

also exam<strong>in</strong><strong>in</strong>g the cost and benefits of treatments.<br />

For patients with cancer, cl<strong>in</strong>ical cancer research has<br />

two benefits: For one, participation <strong>in</strong> cl<strong>in</strong>ical trials<br />

gives the patient early access to new treatments. For<br />

another, treatment quality is the highest at <strong>in</strong>stitutions<br />

that conduct cl<strong>in</strong>ical studies, as a recent study<br />

on breast cancer treatment <strong>in</strong> <strong>Switzerland</strong> showed<br />

[1].<br />

S<strong>in</strong>ce also medium-sized and large hospitals are fre-<br />

quently not able to conduct a research project by<br />

themselves, cl<strong>in</strong>ical cancer research <strong>in</strong> <strong>Switzerland</strong><br />

depends upon good network<strong>in</strong>g of the research<br />

groups and centres. For many years now, this task<br />

has been taken on by the Swiss Group for Cl<strong>in</strong>ical<br />

<strong>Cancer</strong> <strong>Research</strong> (SAKK) for adults and by the Swiss<br />

Paediatric Oncology Group (SPOG) for children. The<br />

activities of the two non-profit organizations are<br />

funded for the most part by research grants from the<br />

Swiss government (State Secretariat for Education<br />

Prof. Beat Thürlimann, MD<br />

Head of the Breast Centre at the Cantonal Hospital of St Gallen and president of the Swiss Group<br />

for Cl<strong>in</strong>ical <strong>Cancer</strong> <strong>Research</strong> (SAKK)<br />

Arnoud Templeton, MD<br />

Senior physician at the Cantonal Hospital of St Gallen and medical advisor of the Swiss Group<br />

for Cl<strong>in</strong>ical <strong>Cancer</strong> <strong>Research</strong> (SAKK)<br />

115

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