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Cancer Research in Switzerland - Krebsliga Schweiz

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<strong>Research</strong> awards:<br />

Besides support<strong>in</strong>g research through fund<strong>in</strong>g<br />

projects, bursaries, and organizations, the Swiss<br />

<strong>Cancer</strong> League regularly gives the Robert Wenner<br />

Award for outstand<strong>in</strong>g research work. In addition,<br />

each year the Scientific Office of the Swiss <strong>Cancer</strong><br />

League organizes the call for research grant<br />

applications and the evaluation of proposals submitted<br />

for the SWISS BRIDGE AWARD.<br />

With the award<strong>in</strong>g of research prizes, the recipients<br />

are recognized for their excellent work <strong>in</strong> cancer research.<br />

For the researchers, this recognition means<br />

both honour for their previous achievements and<br />

<strong>in</strong>centive for future research efforts. As the greatest<br />

part of the award money must be <strong>in</strong>vested <strong>in</strong> cancer<br />

research, research awards allow the recipients to<br />

cont<strong>in</strong>ue their work or to <strong>in</strong>itiate new projects. For<br />

the Swiss <strong>Cancer</strong> League the award<strong>in</strong>g of research<br />

prizes is also a way to <strong>in</strong>form the public about outstand<strong>in</strong>g<br />

<strong>in</strong>dustry-<strong>in</strong>dependent cancer research.<br />

Robert Wenner Award<br />

Robert Wenner, a gynaecologist <strong>in</strong> Basel who died<br />

<strong>in</strong> 1979, endowed the Robert Wenner Award to<br />

support cancer researchers under the age of 45.<br />

The prize was awarded for the first time <strong>in</strong> 1985.<br />

The award w<strong>in</strong>ners receive CHF 100,000, with<br />

CHF 80,000 earmarked for an ongo<strong>in</strong>g project and<br />

CHF 20,000 as discretionary funds. In 2010 the<br />

Robert Wenner Award was given to Prof. Dr. Melody<br />

Swartz at the Swiss Federal Institute of Technology<br />

Lausanne (EPFL) for her excellent work <strong>in</strong> basic research<br />

on tumour metastasis. No prize was awarded<br />

<strong>in</strong> 2009.<br />

Honour<strong>in</strong>g outstand<strong>in</strong>g cancer researchers<br />

Interdiscipl<strong>in</strong>ary cancer researcher<br />

Melody Swartz is a bioeng<strong>in</strong>eer who <strong>in</strong>tegrates different<br />

modern scientific discipl<strong>in</strong>es <strong>in</strong> her research.<br />

Together with her team she comb<strong>in</strong>es cell biology,<br />

biochemistry, physiology, bio<strong>in</strong>formatics, and eng<strong>in</strong>eer<strong>in</strong>g<br />

to study cancer. Her <strong>in</strong>terest centres on the<br />

lymphatic system and, specifically, on how tumour<br />

cells behave <strong>in</strong> the lymphatic system. The lymphatic<br />

system, which works with the circulatory system,<br />

is made up of lymph nodes and lymphatic vessels <strong>in</strong><br />

which lymph fluid circulates. The lymphatic system<br />

transports pathogens to the lymph nodes, where<br />

antibodies are produced and an immune response is<br />

mounted. The immune response thus depends on the<br />

lymphatic system.<br />

Cunn<strong>in</strong>g cancer cells<br />

It is known that cancer cells also utilize lymphatic<br />

vessels to spread through the body and form metastases<br />

at new sites. However, this process is still largely<br />

unknown. Among other th<strong>in</strong>gs, Swartz is study<strong>in</strong>g<br />

how cancer cells move <strong>in</strong>to the lymph vessels. It appears<br />

that tumours are able to stimulate the growth<br />

of the lymph vessels so that cancer cells can <strong>in</strong>vade<br />

them. Also, the lymph vessels appear to actively<br />

support the tumour cells <strong>in</strong> this process. The immune<br />

system is fooled, and the cancer cells evade the<br />

immune defence.

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