Cancer Research in Switzerland - Krebsliga Schweiz
Cancer Research in Switzerland - Krebsliga Schweiz
Cancer Research in Switzerland - Krebsliga Schweiz
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42<br />
S<strong>in</strong>ce 2003 the Foundation <strong>Cancer</strong> <strong>Research</strong> <strong>Switzerland</strong><br />
(formerly Oncosuisse) has supported translational<br />
and cl<strong>in</strong>ical research with two fund<strong>in</strong>g programmes:<br />
Collaborative <strong>Cancer</strong> <strong>Research</strong> Projects<br />
(CCRP) and International Cl<strong>in</strong>ical <strong>Cancer</strong> <strong>Research</strong><br />
Groups (ICP). The aim of both the CCRP and ICP is<br />
to support collaboration among different research<br />
discipl<strong>in</strong>es and <strong>in</strong>stitutes at the national level – and <strong>in</strong><br />
the case of the ICP at the <strong>in</strong>ternational level.<br />
Collaborative <strong>Cancer</strong> <strong>Research</strong> Projects (CCRP)<br />
<strong>Cancer</strong> research is a complex undertak<strong>in</strong>g, especially<br />
due to the enormous advances <strong>in</strong> molecular genetics<br />
<strong>in</strong> recent decades. Today it is impossible for <strong>in</strong>dividual<br />
discipl<strong>in</strong>es or research teams to have an overview<br />
of this complexity. Central questions can only<br />
be tackled with close cooperation among various<br />
specialist areas and <strong>in</strong>stitutes. And it often takes<br />
many years or decades until a discovery <strong>in</strong> the laboratory<br />
f<strong>in</strong>ally results <strong>in</strong> a cl<strong>in</strong>ical application for patients.<br />
The CCRP are multidiscipl<strong>in</strong>ary research collabora-<br />
tions with a longer-term duration of five or more<br />
years. The focus is on support<strong>in</strong>g translational research<br />
studies that shorten the way from the laboratory<br />
to the hospital bed and thus seek to boost medical<br />
progress. The research projects are often complex<br />
and made up of several subprojects that are conducted<br />
at different <strong>in</strong>stitutes. The aim is for diverse<br />
specialists <strong>in</strong> research and medic<strong>in</strong>e to pursue a common<br />
objective, exchange their ideas, expertise, and<br />
f<strong>in</strong>d<strong>in</strong>gs, and <strong>in</strong> this way to improve and accelerate<br />
the knowledge ga<strong>in</strong>.<br />
Programme research: Support<strong>in</strong>g translational and<br />
cl<strong>in</strong>ical research<br />
Kurt Bodenmüller<br />
Communications manager at the Scientific Office, Swiss <strong>Cancer</strong> League<br />
International Cl<strong>in</strong>ical <strong>Cancer</strong> <strong>Research</strong> Groups<br />
(ICP)<br />
In contrast to basic research <strong>in</strong> <strong>Switzerland</strong>, which is<br />
among the world’s best, cl<strong>in</strong>ical cancer research <strong>in</strong><br />
this country is faced with a number of political, structural,<br />
and monetary difficulties. Over the last three<br />
decades, this has caused Swiss cl<strong>in</strong>ical research to<br />
drop down <strong>in</strong>to the midfield <strong>in</strong> an <strong>in</strong>ternational<br />
comparison. Support<strong>in</strong>g cl<strong>in</strong>ical research is therefore<br />
a press<strong>in</strong>g concern not only for the Swiss <strong>Cancer</strong><br />
League and the Foundation Swiss <strong>Cancer</strong> <strong>Research</strong>.<br />
The ICP are cl<strong>in</strong>ical research groups <strong>in</strong> which re-<br />
searchers and physicians <strong>in</strong> several countries work<br />
together. These <strong>in</strong>ternational research projects have<br />
their centres <strong>in</strong> <strong>Switzerland</strong>, which means that they<br />
are coord<strong>in</strong>ated and managed from with<strong>in</strong> <strong>Switzerland</strong>.<br />
A research group <strong>in</strong> the ICP programme receives<br />
fund<strong>in</strong>g of maximum CHF 200,000 per year,<br />
or a total of CHF 800,000 over the four years of the<br />
project duration.<br />
S<strong>in</strong>ce the fund<strong>in</strong>g launch, total grants of CHF 14.7<br />
million have been provided for programme research<br />
(<strong>in</strong> the period 2004 to 2010), of which CHF 10.1 million<br />
went to six CCRP and CHF 4.6 million went to<br />
seven ICP. The CCRP, which earmarked large funds,<br />
were discont<strong>in</strong>ued <strong>in</strong> 2009 <strong>in</strong> favour of the better