Cancer Research in Switzerland - Krebsliga Schweiz

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Epidemiological research
Presentation of approved research projects in 2009/2010
Bordoni Andrea | Indicators of quality of cancer care
in Southern Switzerland (KFS 02668-08-2010)
Duration: 01.01.2011– 01.01.2014
Study design
A prospective descriptive population-based study conducted
in a three-year time period at Ticino Cancer Registry.
Aims
To identify a panel of specific quality of cancer care
(QoCC) indicators concerning three cancers (colorectal,
prostate, ovary/uterus), so as to assess the quality of the
diagnostic and therapeutic process offered in Canton
Ticino; to promote a culture of QoCC among health care
providers; and to obtain improved patient outcomes in the
long term.
Methods
Specific project research boards will be formed for each
type of tumour and the indicators identified will refer to
all incident cases occurring from 2011–2013 in Canton Ticino.
Potential patient benefit
All incident patients resident in Canton Ticino according
to the inhabitants control database and diagnosed from
2011–2013, regardless of age, will be included. We expect
to collect information for 220, 240 and 70 patients per
year with colorectal, prostate and ovarian/uterine cancers,
respectively (for a total number of 1,590 cases for
the 3-year study period).
Project coordinator
Dr. Andrea Bordoni
Registro cantonale dei tumori
Istituto cantonale di patologia (ICP)
Via in Selva 24
CH-6601 Locarno
Phone +41 (0)91 816 08 23
Fax +41 (0)91 816 08 29
andrea.bordoni@ti.ch
Bouchardy Christine | Impact of genetic factors in
breast cancer occurrence, treatment and outcome using
population-based data from the first Familial breast
cancer registry in Switzerland (KFS 02544-02-2010)
Duration: 01.08.2010 – 01.08.2012
Breast cancer is a public health priority in Switzerland.
Family history is one of the major risk factors for breast
cancer. To perform innovative studies on the effect of hereditary
factors on breast cancer occurrence and outcome,
we set up the first and unique Familial breast cancer
registry in Switzerland, which currently contains
validated family histories of cancer for more than 6,000
patients.
Objectives of the study
The objectives of our study are to compare pathological
characteristics of cancers occurring in the same family and
to evaluate the concordance of prognosis between firstdegree
relatives with breast cancer.
Methods
We will compare tumour characteristics between women
with breast cancer belonging to the same family, and
investigate whether the mother or sister’s prognosis influences
the patient’s prognosis.
Potential patient benefit
These studies will allow to a better understanding of the
genetic factors influencing disease prognosis and make it
possible in the near future to improve surveillance and
care of women with high risk breast cancer.
Project coordinator
Prof. Dr Christine Bouchardy
Registre genevois des tumeurs
Institut de médecine sociale et préventive
Département de médecine et santé communautaire
Université de Genève
Bd de la Cluse 55
CH-1205 Genève
Phone +41 (0)22 379 49 50
christine.bouchardymagnin@unige.ch
Clough-Gorr Kerri | The Swiss National Cohort (SNC)
and the National Institute for Cancer Epidemiology and
Registration (NICER) – Cancer Epidemiology Study,
1990–2008 (KFS 02553-02-2010)
Duration: 01.10.2010 – 01.10.2013
Objective
To answer critical questions related to the burden of cancer
in Switzerland.
Methods
The study population includes the census-based population
of Swiss adults (≥ age 20) living in NICER cancer registry
areas (Appenzell, Basel, Geneva, Glarus, Graubünden,
Neuchâtel, St Gallen, Ticino, Valais, Vaud, Zurich). Participants
are followed forward in time 1990–2008 with up to
18 years of follow-up for cancer outcomes. Information
will be collected on incidence, survival, prevalence of cancer,
and socio-demographic, lifestyle and geo-cultural
characteristics.
Aims:
1) Examine gender-specific trends in cancer outcomes.
2) Evaluate gender-specific socio-demographic factors
associated with cancer outcomes.
3) Identify gender-specific lifestyle factors associated
with cancer outcomes.
4) Create a multi-institution multidisciplinary research
board to promote cancer epidemiology research based
on the SNC-NICER study platform.