Cancer Research in Switzerland - Krebsliga Schweiz

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42 Since 2003 the Foundation Cancer Research Switzerland (formerly Oncosuisse) has supported translational and clinical research with two funding programmes: Collaborative Cancer Research Projects (CCRP) and International Clinical Cancer Research Groups (ICP). The aim of both the CCRP and ICP is to support collaboration among different research disciplines and institutes at the national level – and in the case of the ICP at the international level. Collaborative Cancer Research Projects (CCRP) Cancer research is a complex undertaking, especially due to the enormous advances in molecular genetics in recent decades. Today it is impossible for individual disciplines or research teams to have an overview of this complexity. Central questions can only be tackled with close cooperation among various specialist areas and institutes. And it often takes many years or decades until a discovery in the laboratory finally results in a clinical application for patients. The CCRP are multidisciplinary research collabora- tions with a longer-term duration of five or more years. The focus is on supporting translational research studies that shorten the way from the laboratory to the hospital bed and thus seek to boost medical progress. The research projects are often complex and made up of several subprojects that are conducted at different institutes. The aim is for diverse specialists in research and medicine to pursue a common objective, exchange their ideas, expertise, and findings, and in this way to improve and accelerate the knowledge gain. Programme research: Supporting translational and clinical research Kurt Bodenmüller Communications manager at the Scientific Office, Swiss Cancer League International Clinical Cancer Research Groups (ICP) In contrast to basic research in Switzerland, which is among the world’s best, clinical cancer research in this country is faced with a number of political, structural, and monetary difficulties. Over the last three decades, this has caused Swiss clinical research to drop down into the midfield in an international comparison. Supporting clinical research is therefore a pressing concern not only for the Swiss Cancer League and the Foundation Swiss Cancer Research. The ICP are clinical research groups in which re- searchers and physicians in several countries work together. These international research projects have their centres in Switzerland, which means that they are coordinated and managed from within Switzerland. A research group in the ICP programme receives funding of maximum CHF 200,000 per year, or a total of CHF 800,000 over the four years of the project duration. Since the funding launch, total grants of CHF 14.7 million have been provided for programme research (in the period 2004 to 2010), of which CHF 10.1 million went to six CCRP and CHF 4.6 million went to seven ICP. The CCRP, which earmarked large funds, were discontinued in 2009 in favour of the better
manageable funding of individual projects. ICP calls for proposals are also no longer being announced. Instead, since 2009 funding has been given to clinical research institutions via research contracts and agreements (see here the article on research funding on page 6).
Page 1 and 2: Cancer Research in Switzerland A pu
Page 3 and 4: Cancer Research in Switzerland
Page 5 and 6: Basic biomedical research 55 Cancer
Page 7 and 8: policy work and was in charge of de
Page 9 and 10: The main focus of the research fund
Page 11 and 12: gramme research funding decreased b
Page 13 and 14: Table 2 Distribution of funds for i
Page 15 and 16: Funding patient-centred research Pa
Page 17 and 18: value was not clearly discernible.
Page 19 and 20: New organization of the Foundation
Page 21 and 22: The board of the Foundation Cancer
Page 23 and 24: The president of the Scientific Com
Page 25 and 26: Prof. Martin Pruschy, PhD Departmen
Page 27 and 28: Swartz wants to find out how tumour
Page 29 and 30: The scientific and medical research
Page 31 and 32: 3. The original order/sequence of t
Page 33 and 34: As a federation, the Cancer League
Page 35 and 36: List of funded research projects, i
Page 37 and 38: Zippelius Alfred | 2009: CHF 100,00
Page 39 and 40: Kridel Robert | 2010: CHF 100,000.-
Page 41 and 42: Thurgau Cancer League Biotechnologi
Page 43: Weller Michael | 2010: CHF 65,828.-
Page 47 and 48: enhances breast cancer cell motilit
Page 49 and 50: Rüegg Curzio et al. | Tumor-mediat
Page 51 and 52: International Clinical Cancer Resea
Page 53 and 54: in PHIV were shown for Hodgkin’s
Page 55: Zucca Emanuele et al. | Internation
Page 58 and 59: 56 “hierarchical structure” of
Page 60 and 61: 58 the attempt should be made to st
Page 62 and 63: 60 Gönczy Pierre | KLS 0202402
Page 64 and 65: 62 Romero Pedro | OCS 020110220
Page 66 and 67: 64 Beermann Friedrich | In vivo scr
Page 68 and 69: 66 Christofori Gerhard | Podoplanin
Page 70 and 71: 68 Frei Christian | The function of
Page 72 and 73: 70 cell, this novel mechanism serve
Page 74 and 75: 72 Results The induction of viral p
Page 76 and 77: 74 Hübscher Ulrich | Repair of oxi
Page 78 and 79: 76 Methods and experimental approac
Page 80 and 81: 78 of cMyc and/or NMyc and demo
Page 82 and 83: 80 In summary, this work improves o
Page 84 and 85: 82 Pruschy Martin | Microtubule int
Page 86 and 87: 84 Renner Christoph | Selective inh
Page 88 and 89: 86 Goal Here we build on these obse
Page 90 and 91: 88 by TDG prevents efficient downst
Page 92 and 93: 90 To address these questions, we a
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92 Translational relevance The resu
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94 Grünberg Jürgen | KFS 025460
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96 Tschan Mario P. | KFS 0248608
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98 Boyman Onur | Preclinical testin
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100 Constam Daniel | Role of activi
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102 this study we will examine the
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104 Janscak Pavel | Study of the ro
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106 Müller Anne | The molecular pa
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108 Radtke Freddy | The role of Not
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110 Schär Primo | DNA repair, epig
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112 In this project we will investi
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114
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116 and Research). Other financial
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118 be totally unaffordable for aca
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120 Clinical research List of compl
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122 Hunger Robert E. | OCS 02262-08
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124 Clinical research Presentation
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126 Benhattar Jean | Identification
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128 Bertoni Francesco | Genome-wide
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130 Interpretation ESA treatment in
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132 Our results could pave the way
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134 new drugs that specifically tar
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136 slides in two different concent
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138 Conclusions A strong network of
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140 tions introduced to ARE motifs
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142 Müller Beatrice U. | The maste
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144 A novel method was developed fo
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146 (SAKK 35-98) the Swiss Group fo
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148 Timmermann Beate | Prospective
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150 recurrence of the disease, we a
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152 Zucca Emanuele | A prospective
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154 Heinimann Karl | KFS 02489-08-2
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156 Riggi Nicolò | BIL KFS 02717-0
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158 activity at the single cell lev
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160 Our research projects aim at un
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162 Körner Meike | In vitro evalua
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164 Nadal David | Is endemic Burkit
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166 (> 50.000/patient). For their a
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168 Zeller Rolf | Functional analys
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170
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172 area of health services researc
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174 The financing of palliative car
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176 National Strategy for Palliativ
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178 Psychosocial research List of c
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180 Within the patient group, level
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182 Further, the results suggest th
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184 It is in this context that the
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186 Recommendation Female spouses o
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188 Psychosocial research Presentat
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190 rates communication skills rema
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Epidemiological research Epidemiolo
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data from cancer registries. In the
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The importance of cancer registries
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Ess Silvia | Patterns of care and s
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Epidemiological research List of ap
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Impact This work will serve as the
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Thürlimann Beat | Management of br
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Cancer Research in Switzerland - Krebsliga Schweiz

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