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Linfoma no Hodgkin en adultos: Tratamiento (PDQ®) - National ...

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<strong>Linfoma</strong> <strong>no</strong> <strong>Hodgkin</strong> <strong>en</strong> <strong>adultos</strong>: Tratami<strong>en</strong>to (<strong>PDQ®</strong>) - <strong>National</strong> Cancer Institute<br />

<strong>no</strong>n-<strong>Hodgkin</strong> lymphoma , indol<strong>en</strong>t, stage III adult <strong>no</strong>n-<strong>Hodgkin</strong> lymphoma y indol<strong>en</strong>t, stage IV adult <strong>no</strong>n-<br />

<strong>Hodgkin</strong> lymphoma 41 . La lista de <strong>en</strong>sayos se puede reducir aun más por la ubicación donde se realizan, los<br />

medicam<strong>en</strong>tos que se utilizan, el tipo de interv<strong>en</strong>ción y otros criterios. Nota: los resultados obt<strong>en</strong>idos solo estarán<br />

disponibles <strong>en</strong> inglés.<br />

Asimismo, se dispone de información g<strong>en</strong>eral sobre <strong>en</strong>sayos clínicos <strong>en</strong> el portal de Internet del NCI 28 .<br />

Bibliografía<br />

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[PUBMED Abstract]<br />

2. Ardeshna KM, Smith P, Norton A, et al.: Long-term effect of a watch and wait policy versus immediate<br />

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trial. Lancet 362 (9383): 516-22, 2003. [PUBMED Abstract]<br />

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4. Brice P, Bastion Y, Lepage E, et al.: Comparison in low-tumor-burd<strong>en</strong> follicular lymphomas betwe<strong>en</strong> an<br />

initial <strong>no</strong>-treatm<strong>en</strong>t policy, prednimustine, or interferon alfa: a randomized study from the Groupe d'Etude<br />

des Lymphomes Folliculaires. Groupe d'Etude des Lymphomes de l'Adulte. J Clin Oncol 15 (3): 1110-7,<br />

1997. [PUBMED Abstract]<br />

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Inst 98 (18): 1263-5, 2006. [PUBMED Abstract]<br />

6. Smalley RV, Anders<strong>en</strong> JW, Hawkins MJ, et al.: Interferon alfa combined with cytotoxic chemotherapy for<br />

pati<strong>en</strong>ts with <strong>no</strong>n-<strong>Hodgkin</strong>'s lymphoma. N Engl J Med 327 (19): 1336-41, 1992. [PUBMED Abstract]<br />

7. Solal-Céligny P, Lepage E, Brousse N, et al.: Doxorubicin-containing regim<strong>en</strong> with or without interferon<br />

alfa-2b for advanced follicular lymphomas: final analysis of survival and toxicity in the Groupe d'Etude des<br />

Lymphomes Folliculaires 86 Trial. J Clin Oncol 16 (7): 2332-8, 1998. [PUBMED Abstract]<br />

8. Anders<strong>en</strong> JW, Smalley RV: Interferon alfa plus chemotherapy for <strong>no</strong>n-<strong>Hodgkin</strong>'s lymphoma: five-year<br />

follow-up. N Engl J Med 329 (24): 1821-2, 1993. [PUBMED Abstract]<br />

9. Hag<strong>en</strong>beek A, Carde P, Meerwaldt JH, et al.: Maint<strong>en</strong>ance of remission with human recombinant interferon<br />

alfa-2a in pati<strong>en</strong>ts with stages III and IV low-grade malignant <strong>no</strong>n-<strong>Hodgkin</strong>'s lymphoma. European<br />

Organization for Research and Treatm<strong>en</strong>t of Cancer Lymphoma Cooperative Group. J Clin Oncol 16 (1):<br />

41-7, 1998. [PUBMED Abstract]<br />

10. Aviles A, Duque G, Talavera A, et al.: Interferon alpha 2b as maint<strong>en</strong>ance therapy in low grade malignant<br />

lymphoma improves duration of remission and survival. Leuk Lymphoma 20 (5-6): 495-9, 1996. [PUBMED<br />

Abstract]<br />

11. Arranz R, García-Alfonso P, Sobri<strong>no</strong> P, et al.: Role of interferon alfa-2b in the induction and maint<strong>en</strong>ance<br />

treatm<strong>en</strong>t of low-grade <strong>no</strong>n-<strong>Hodgkin</strong>'s lymphoma: results from a prospective, multic<strong>en</strong>ter trial with double<br />

randomization. J Clin Oncol 16 (4): 1538-46, 1998. [PUBMED Abstract]<br />

12. Fisher RI, Dana BW, LeBlanc M, et al.: Interferon alpha consolidation after int<strong>en</strong>sive chemotherapy does<br />

<strong>no</strong>t prolong the progression-free survival of pati<strong>en</strong>ts with low-grade <strong>no</strong>n-<strong>Hodgkin</strong>'s lymphoma: results of<br />

the Southwest Oncology Group randomized phase III study 8809. J Clin Oncol 18 (10): 2010-6, 2000.<br />

[PUBMED Abstract]<br />

13. Cole BF, Solal-Céligny P, Gelber RD, et al.: Quality-of-life-adjusted survival analysis of interferon alfa-2b<br />

treatm<strong>en</strong>t for advanced follicular lymphoma: an aid to clinical decision making. J Clin Oncol 16 (7): 2339-<br />

44, 1998. [PUBMED Abstract]<br />

14. Ozer H, Wiernik PH, Giles F, et al.: Recombinant interferon-alpha therapy in pati<strong>en</strong>ts with follicular<br />

lymphoma. Cancer 82 (10): 1821-30, 1998. [PUBMED Abstract]<br />

15. All<strong>en</strong> IE, Ross SD, Bord<strong>en</strong> SP, et al.: Meta-analysis to assess the efficacy of interferon-alpha in pati<strong>en</strong>ts<br />

with follicular <strong>no</strong>n-<strong>Hodgkin</strong>'s lymphoma. J Immu<strong>no</strong>ther 24 (1): 58-65, 2001 Jan-Feb. [PUBMED Abstract]<br />

16. Cheson BD: The curious case of the baffling biological. J Clin Oncol 18 (10): 2007-9, 2000. [PUBMED<br />

Abstract]<br />

17. Rohatiner AZ, Gregory WM, Peterson B, et al.: Meta-analysis to evaluate the role of interferon in follicular<br />

lymphoma. J Clin Oncol 23 (10): 2215-23, 2005. [PUBMED Abstract]<br />

file:///Users/mauriciolema/Docum<strong>en</strong>ts/MLMGuias_09_<strong>Linfoma</strong>No<strong>Hodgkin</strong>.webarchive<br />

29/09/11 6:15<br />

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