Imprinting-clin 2011.pdf - Università degli Studi di Torino
Imprinting-clin 2011.pdf - Università degli Studi di Torino
Imprinting-clin 2011.pdf - Università degli Studi di Torino
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<strong>Imprinting</strong> e tumore <strong>di</strong> Wilms<br />
Molecular defect Non BWS-Wilms BWS Wilms<br />
IC1<br />
hypermethylation<br />
with microdeletion<br />
IC1<br />
hypermethylation<br />
without microdeletion<br />
Loss of maternal<br />
allele (UPD or LOH)<br />
0 2<br />
10 2<br />
18 2<br />
No defect 12 0
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