Tumorile cardiopericardice Prof Dr Grigore Tinica, Dr. Lutea Mirela ...

Four-chamber echocardiograph of a left atrial myxoma in a 71-year-old woman, showing a mass on the left side of the heart
(A) projecting from the atrial septum through the mitral valve into the left ventricle. B, Gross photograph of the left atrial
myxoma that was surgically excised from the same woman. Grossly, the tumor is a pedunculated, variegated mass with a
friable, gelatinous texture.C, Hematoxylin and eosin staining of the loose, proteoglycan-rich tumor (×200). The tumor is highly
vascular; with vessels containing red blood cells admixed with lipidic cells present in a network throughout the tumor matrix
(arrow). Immunohistochemical staining for vessels was positive for alpha smooth muscle actin, CD 34, and CD 31 (D, E, and
F, respectively; ×400). Staining for leukocyte common antigen is positive for mononuclear cells (G; ×400). Staining for CD 68
shows several macrophages (H; ×400), some of which are hemosiderin laden, reflecting previous hemorrhage, a common
occurrence in myxomas.
Mixoamele atriului stang reprezinta 75% dintre mixoamele cardiace, iar unele dintre ele
pot avea arii importante de calcificari. Notiunea de litomixom este aplicabila tumorilor cu
calcificari importante. Se identifica mineralizari partiale si mineralizarea completa, cu metaplazie
osoasa si cartilaginoasa. Termenul de mixom cardiac pietrificat desemneaza mixoamele inactive
care incep sa semene cu niste pietre prin impregnarea cu minerale. Majoritatea mixoamelor
cardiace au un diametru de aproximativ 8 cm. Sunt mentionate mixoame cardiace cu dimensiuni
variabile de la 0,8 la 8 cm, cantarind intre 8 si 175 g. Media greutatii unui mixom cardiac este de
35g. Termenul de mixom cardiac ocult a fost atribuit unui caz care masura 1 mm.
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