SODIUM CARBONATE CAS N°: 497-19-8 - UNEP Chemicals
SODIUM CARBONATE CAS N°: 497-19-8 - UNEP Chemicals
SODIUM CARBONATE CAS N°: 497-19-8 - UNEP Chemicals
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OECD SIDS <strong>SODIUM</strong> <strong>CARBONATE</strong><br />
5. TOXICITY Id <strong>497</strong>-<strong>19</strong>-8<br />
Date <strong>19</strong>.02.2003<br />
METHOD OF CALCULATION: Not reported.<br />
ANALYTICAL METHODS: Not reported.<br />
Result : MORTALITY:<br />
No details reported.<br />
CLINICAL SIGNS: Not reported.<br />
NECROPSY FINDINGS: Not reported.<br />
POTENTIAL TARGET ORGANS: Not reported.<br />
SEX-SPECIFIC DIFFERENCES: Not reported.<br />
Test condition : TEST ORGANISMS:<br />
No details reported.<br />
ADMINISTRATION:<br />
No details reported.<br />
EXAMINATIONS: Not reported.<br />
Test substance : SOURCE: Not reported.<br />
PURITY: Not reported.<br />
IMPURITY/ADDITIVE/ETC.: Not reported.<br />
ANY OTHER INFORMATION: Not reported.<br />
Reliability : (4) not assignable<br />
Only stated in secondary literature.<br />
14.02.2003 (13) (20)<br />
5.1.4 ACUTE TOXICITY, OTHER ROUTES<br />
5.2.1 SKIN IRRITATION<br />
Species : rabbit<br />
Concentration : .5 g<br />
Exposure : Occlusive<br />
Exposure time : 4 hour(s)<br />
Number of animals : 6<br />
Vehicle : other<br />
PDII : 0<br />
Result : not irritating<br />
Classification : not irritating<br />
Method : Directive 84/449/EEC, B.4 "Acute toxicity (skin irritation)"<br />
Year : <strong>19</strong>85<br />
GLP : no<br />
Test substance : other TS: sodium carbonate<br />
Method : METHOD FOLLOWED: According OECD guideline 404, with two main<br />
deviations, and several minor ones.<br />
DEVIATIONS FROM<br />
OECD GUIDELINE 404: Test substance was not moistened with water to<br />
ensure good contact between skin and test substance; patch was occlusive<br />
instead of semi-occlusive.<br />
Minor deviations included small differences in housing conditions and no<br />
other toxic effects have been observed.<br />
GLP: A Quality Assurance Unit statement was included<br />
STATISTICAL METHODS: Not reported.<br />
METHOD OF CALCULATION: Not reported.<br />
ANALYTICAL METHODS: Not reported.<br />
Result : AVERAGE SCORE<br />
- Erythema: 0<br />
- Edema: 0<br />
REVERSIBILITY: Not relevant<br />
OTHER EFFECTS: No<br />
Test condition<br />
62<br />
: TEST ANIMALS:<br />
- Strain: White New Zealand<br />
- Sex: Not reported.<br />
- Source: Harald Schriever, Rabbit farm, Germany.<br />
<strong>UNEP</strong> Publications
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