SODIUM CARBONATE CAS N°: 497-19-8 - UNEP Chemicals

OECD SIDS SODIUM CARBONATE
5. TOXICITY Id 497-19-8
Date 19.02.2003
- Source: Harald Schriever, Rabbit farm, Germany.
- Age: Not reported.
- Weight at study initiation: 2.4 - 2.6 kg
- Number of animals: 6
- Controls: Included but not described.
ADMINISTRATION/EXPOSURE
- Preparation of test substance: No preparation
- Area of exposure: Shaved backskin 2.5 x 2.5 cm.
- Occlusion: Yes
- Vehicle: Not reported.
- Concentration in vehicle: Not reported.
- Total volume applied: 0.5 g
- Postexposure period: Up to 72 hr.
- Removal of test substance: Washed with water.
IN VITRO TEST SYSTEM
Not relevant.
EXAMINATIONS
- Scoring system: Draize scheme
- Examination time points: 30 and 60 min, 24, 48, and 72 hr.
Test substance : SOURCE: Chem . Fabrik Kalk GmbH, Köln, Germany
PURITY: Not reported.
IMPURITY/ADDITIVE/ETC.: Not reported.
ANY OTHER INFORMATION: Name (in german) of test substance:
"Leichte calc. Soda" (Eng.: Light calcined soda)
Reliability : (1) valid without restriction
Guideline study with minor deviations.
17.02.2003 (5)
Species : rabbit
Concentration : .5 g
Exposure : Occlusive
Exposure time : 24 hour(s)
Number of animals : 6
Vehicle : other: none
PDII : 0
Result : not irritating
Classification : not irritating
Method : other: EPA 16 CFR 1500.3
Year : 1978
GLP : no
Test substance : other TS: The test substance was sodium carbonate monohydrate.
Method : METHOD FOLLOWED: 16 CFR 1500.3
DEVIATIONS FROM GUIDELINE: Not reported.
GLP: No
STATISTICAL METHODS: Not reported.
METHOD OF CALCULATION: Not reported.
ANALYTICAL METHODS: Not reported.
Result : AVERAGE SCORE
- Erythema: 0.
- Edema: 0.
REVERSIBILITY: Not reported.
OTHER EFFECTS: Not reported.
The primary dermal irritation index was 0.
Test condition : TEST ANIMALS: Rabbits.
- Strain: New Zealand White Albino.
- Sex: Not reported.
- Source: Not reported.
- Age: Not reported.
- Weight at study initiation: 2.2-2.7 kg.
- Number of animals: 6.
- Controls: Not reported.
UNEP Publications 63