2011 ADA Posters 1261-2041.indd - Diabetes
2011 ADA Posters 1261-2041.indd - Diabetes
2011 ADA Posters 1261-2041.indd - Diabetes
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Integrated Physiology/<br />
Obesity<br />
POSTERS<br />
actions in vivo, we generated transgenic mice which specifi cally express the<br />
gene coding for adiponectin receptor 1 (AdR1) in mouse macrophages using<br />
the scavenger receptor A-I gene (SR-AI) enhancer/promoter.<br />
Analyzing this transgenic mouse model, we have determined that AdR1<br />
expression in macrophages was associated with a signifi cantly decreased<br />
cholesterol (45%, p