Dipropylene glycol (SIDS)

OECD SIDS PROPYLENE GLYCOL
4. Ecotoxicity
Id 25265-71-8
Date 30.05.2001
4.1 ACUTE/PROLONGED TOXICITY TO FISH
Type : other: static acute LC50 (TLm)
Species : Carassius auratus (Fish, fresh water)
Exposure period : 24 hour(s)
Unit : mg/l
Analytical monitoring : yes
LC50 : > 5000
Method :
Year : 1978
GLP : no
Test substance : no data
Method : APHA (American Public Health Association) 1971
Fish exposed to serial dilutions of TS with local tap water as the dilution
water source.
Study conducted in 25 L all-glass tanks measuring 42 x 28 x 28 cm at 20 ±
1 ºC.
Fish in the study had an average length of 6.2 ± 0.7 cm and an average
weight of 3.3 ± 1.0 g.
Calculation of LC50 (TLm)
Interpolation from graph of logarithm of concentration vs. percentage
mortality
Remarks: Because this study was conducted before any standardized
guidelines were established, the question of guideline methodology and
GLP conduct is not applicable.
Remark : Original reference not available for review, so methods and results were
described based on a reputable secondary source.
Result : Since the 24-hour LC50 (TLm) was >5,000 mg/L, the study was terminated
at this point.
Source : Lyondell Chemical Co. Houston, Texas
Conclusion : The 24-hour LC50 (TLm) for goldfish was determined to be >5,000 mg/L.
Reliability : (2) valid with restrictions
Details on the test procedure and study results are not provided. Details
on the results of analytical measurement of test substance concentrations
in the test solutions and sample purity is not provided.
Flag : Critical study for SIDS endpoint
23.05.2001 (8)
4.2 ACUTE TOXICITY TO AQUATIC INVERTEBRATES
4.3 TOXICITY TO AQUATIC PLANTS E.G. ALGAE
4.4 TOXICITY TO MICROORGANISMS E.G. BACTERIA
Type : other: static acute EC10
Species : Pseudomonas putida (Bacteria)
Exposure period : 18 hour(s)
Unit : mg/l
Analytical monitoring : yes
EC10 : = 1000
UNEP PUBLICATIONS 61