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Dipropylene glycol (SIDS)

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OECD <strong>SIDS</strong> PROPYLENE GLYCOL<br />

4. Ecotoxicity<br />

Id 25265-71-8<br />

Date 30.05.2001<br />

Test substance: no compositional details given<br />

Exposure Period: 48 hrs<br />

Method: No methodology given.<br />

Clawed toads exposed to serial dilutions of test substance with Dutch<br />

standard water as the dilution water source.<br />

Study conducted in 1 L all-glass covered aquaria with 3-4 week old larvae<br />

at a study temperature of 20 ± 1 ºC.<br />

Calculation of LC50<br />

Calculated as projection from least square linear regression on log<br />

transformed nominal concentration data and probit transformed percent<br />

effect data.<br />

Analytical monitoring: None<br />

Result : Mortality measured after 48 hours of exposure resulted in determination of<br />

an LC50 of 3,181 mg/L.<br />

Source : Lyondell Chemical Co. Houston, Texas<br />

Conclusion : The 48-hour LC50 (TLm) for the clawed toad was determined to be 3,181<br />

mg/L.<br />

Reliability : (2) valid with restrictions<br />

Details on the test procedure and study results are not provided. No<br />

analytical measurement of test substance concentrations in the test<br />

solutions or sample purity were conducted.<br />

Flag : Critical study for <strong>SIDS</strong> endpoint<br />

23.05.2001 (14)<br />

UNEP PUBLICATIONS 63

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