How to investigate levels of Adherence to antiretroviral ... - INRUD
How to investigate levels of Adherence to antiretroviral ... - INRUD
How to investigate levels of Adherence to antiretroviral ... - INRUD
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<strong>How</strong> <strong>to</strong> Investigate <strong>Adherence</strong> <strong>to</strong> Antiretroviral Treatment:<br />
An Indica<strong>to</strong>r-Based Approach<br />
practice, the recall period they may have asked about could vary from their adherence<br />
yesterday <strong>to</strong> since the last clinic visit.<br />
The indica<strong>to</strong>r chosen here using self-reporting is the same as used from exit interviews.<br />
Self Report 1.<br />
Percentage <strong>of</strong> patients with full adherence <strong>to</strong> ART (i.e., no doses missed<br />
in the recall period, which is three days in the <strong>INRUD</strong>-IAA methodology)<br />
Rationale<br />
Source <strong>of</strong> data<br />
Data collection<br />
Perfect (or > 95%) adherence is the primary treatment goal.<br />
Patient self-report—―In the last 3 days (or at least a standardized number <strong>of</strong><br />
days) have you missed any <strong>of</strong> the ARV doses you were supposed <strong>to</strong> take?‖<br />
(Response: Y/N)<br />
Pharmacy or clinical records based on the same sample <strong>of</strong> 100 patient records<br />
sampled for the core indica<strong>to</strong>rs.<br />
Computation (# <strong>of</strong> patients responding N/# <strong>of</strong> patients asked) × 100.<br />
Comments<br />
Pitfalls<br />
Question can be asked for last 1, 2, 3, 4, or 7 days. For any <strong>of</strong> these periods,<br />
this indica<strong>to</strong>r is the equivalent <strong>of</strong> the 95% adherence rate (missing 1 dose in 7<br />
days is 7.7% <strong>of</strong> doses on a twice daily regimen). Calculation can be the same if<br />
the question is asked for 30 days or for the period since last clinic visit, but<br />
interpretation would differ.<br />
The only hope <strong>of</strong> getting an honest answer is if the interviewer or clinician is<br />
friendly and non-<strong>of</strong>ficious. Interviewers or clinicians need <strong>to</strong> be trained <strong>to</strong> ask<br />
the question in a uniform way.<br />
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