How to investigate levels of Adherence to antiretroviral ... - INRUD

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Chapter 5 Data collection tools and how to modify, print and fill them in Preparing for the facility interview Before carrying out the interview, it is necessary to compile three lists of medicines and doses, each with up to 10 medicines and formulations: Key ARV medicine for adults with dose and formulation. Key ARV medicine for children with dose and formulation. Key non-ARV medicines that should be present in every facility. For the ARV medicines, decisions have to be made on which medicines should be present in all clinics. Therefore, first-line treatments should be included. Second-line medicines should only be included if all facilities are expected to stock them. The paediatric list should only be filled in if the clinic treats children with ARVs. Sample lists are included in the document ‚Questionnaires.xlt‛ and can be modified/adapted to local conditions via the customization section see Customization earlier in this chapter. Table 7. Sample list of needed adult ARVs Adults ARV first-line drug Abbreviation 1 Lamivudine 150 mg tab 3TC 2 Stavudine 40 mg tab D4T 3 Stavudine 30 mg tab D4T 4 Nevirapine 200 mg tab NVP 5 Efavirenz 200 mg tab EFV 6 Efavirenz 600 mg tab EFV 7 ZDV 300 mg + 3TC 150 mg tab ZDV, 3TC 8 9 10 43
How to Investigate Adherence to Antiretroviral Treatment: An Indicator-Based Approach Table 8. Sample list of needed paediatric ARVs Paediatric ARV first-line drug Abbreviation 1 Efavirenz 50 mg or 100 mg tab EFV 2 Efavirenz 30 mg/ml syrup EFV 3 Nevirapine 10 mg/ml syrup NVP 4 Lamivudine 10 mg/ml syrup 3TC 5 Zidovudine 100 mg tab ZDV 6 Zidovudine 10 mg/ml syrup ZDV 7 Stavudine 15 mg tab D4T 8 Stavudine 20 mg tab D4T 9 Stavudine 1 mg/ml syrup D4T 10 The list of expected non-ARV medicines will depend on the system. That list would also depend on the most common opportunistic infections and co-morbidities. If the non-ARV medicines present in a hospital pharmacy are different than for the ART clinic, those medicines would not be counted as being present. If the stock records are incomplete, it may be difficult or impossible to know the number of days that each medicine has been in or out of stock in the last 90 days. The pharmacist, however, may know if there have been any stock outs, in which case you can just ask whether there have been any stock outs in the last three months for each medicine. Table 9. Sample list of key non-ARV medicines Key non-ARV drugs 1 Co-trimoxazole 480 or 960 mg tab 2 Co-trimoxazole 240 mg/5ml susp 3 Fluconazole 150 mg or 200 mg tab 4 Miconazole 20 mg/g oral gel 5 Erythromycin 250 mg or 500 mg tab 6 Nystatin 10,000 IU/ml oral drops 7 Aciclovir 200 mg tab 8 Aciclovir 5% cream 9 Folic acid 5 mg tab 10 44
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