Flavonoid-Drug Interactions: Effects of Flavonoids on ABC ...
Flavonoid-Drug Interactions: Effects of Flavonoids on ABC ...
Flavonoid-Drug Interactions: Effects of Flavonoids on ABC ...
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Involvement <str<strong>on</strong>g>of</str<strong>on</strong>g> GSH in MRP1-mediated transport<br />
ATP<br />
GSSG<br />
MRP1<br />
oxidative<br />
stress<br />
GSH<br />
(reduced)<br />
GSTase<br />
ADP + Pi<br />
GSSG<br />
(oxidized)<br />
GSH<br />
reductase<br />
GSH<br />
c<strong>on</strong>jugate<br />
ATP<br />
ADP + Pi<br />
endogenous<br />
or exogenous<br />
compound<br />
GSH<br />
vincristine<br />
ADP + Pi<br />
ATP<br />
MRP1<br />
GSH<br />
GS-X<br />
MRP1<br />
GSH<br />
+<br />
vincristine<br />
Qingcheng Mao