Flavonoid-Drug Interactions: Effects of Flavonoids on ABC ...
Flavonoid-Drug Interactions: Effects of Flavonoids on ABC ...
Flavonoid-Drug Interactions: Effects of Flavonoids on ABC ...
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Summary<br />
Chrysin and BF did not change topotecan PK in rats or mice<br />
Tentative explanati<strong>on</strong> for the discrepancy: species difference<br />
with respect to inhibiti<strong>on</strong> <str<strong>on</strong>g>of</str<strong>on</strong>g> topotecan<br />
(species difference not seen with mitoxantr<strong>on</strong>e)<br />
Other possibilities could not be excluded, such as involvement<br />
<str<strong>on</strong>g>of</str<strong>on</strong>g> other transporters
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