Final Program - American Society of Gene & Cell Therapy
Final Program - American Society of Gene & Cell Therapy
Final Program - American Society of Gene & Cell Therapy
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Abstract Directory, Saturday, May 18, 2013<br />
Oral Abstract Session 415<br />
Oligonucleotide & RNAi Therapeutics<br />
10:15 AM - 12:15 PM<br />
Room: Ballroom C<br />
509 10:15 AM<br />
Targeted, Multifunctional RNA Therapies for Advanced<br />
Cancers <strong>of</strong> the Prostate<br />
Luiza I. Hernandez, William M. Rockey, Craig A. Howell, Justin P.<br />
Dassie, Frank J. Hernandez, Xiu Y. Liu, Paloma H. Giangrande.<br />
510 10:30 AM<br />
Circulating Plasmid Detection in a Phase I Clinical Trial<br />
<strong>of</strong> Intratumoral Injection <strong>of</strong> pbi-shRNA Nanoplex<br />
Christopher M. Jay, Donald D. Rao, Zhaohui Wang, Neil Senzer,<br />
Phillip B. Maples, John Nemunaitis.<br />
511 10:45 AM<br />
Smooth Muscle <strong>Cell</strong> Targeted RNA Aptamers for the<br />
Treatment <strong>of</strong> Vascular Disease<br />
William H. Thiel, Maysam Takapoo, Shuxia Jiang, Jennifer<br />
Streeter, Bojana Stanic, Xiuying Liu, Francis J. Miller, Jr, Paloma H.<br />
Giangrande.<br />
512 11:00 AM<br />
Long-Term Inhibition <strong>of</strong> miR-122 Signiicantly<br />
Increases Hepatocellular Carcinoma in Multiple Adult<br />
Mouse Models<br />
Jun Xie, Qin Mao, Jia Li, Xia<strong>of</strong>ang Yang, Qin Su, Ran He, Zhong Jiang,<br />
Xia<strong>of</strong>ei Wang, Phillip D. Zamore, Guangping Gao.<br />
513 11:15 AM<br />
In Vitro and In Vivo Effects <strong>of</strong> Composite Calcium<br />
Phosphate and Poly(Lactic-Co-Glycolic Acid) (PLGA)<br />
Nanoparticles Engineered for Enhanced Cancer <strong>Cell</strong><br />
Internalization and Sustained siRNA Release<br />
Lisa A. Tobin, Yili Xie, Su I. Chung, King F. Kwong.<br />
514 11:30 AM<br />
Robust RNAi Enhancement Via Human Argonaute-2<br />
Overexpression from Plasmids, Viral Vectors or <strong>Cell</strong><br />
Lines<br />
Kathleen Boerner, Dominik Niopek, Daniel Gilbert, Konrad Streetz,<br />
Hans-Georg Kraeusslich, Dirk Grimm.<br />
515 11:45 AM<br />
Ultra-Stable Trivalent RNA Nanoparticles for Targeting<br />
to Cancers and HIV-1<br />
Kato Shum, Peixuan Guo, John J. Rossi.<br />
516 12:00 PM<br />
Directed Evolution-Based Dissection <strong>of</strong> the Four Human<br />
Argonaute Proteins<br />
Nina Schuermann, Leonardo Trabucco, Christian Bender, Rob<br />
Russell, Dirk Grimm.<br />
Poster Session III<br />
3:45 PM - 5:45 PM<br />
Room: Exhibit Hall C/D<br />
RNA Virus Vectors<br />
517<br />
Data Mining Methods for Integration Site Analysis in<br />
Hematopoietic Stem <strong>Cell</strong> <strong>Gene</strong> <strong>Therapy</strong> Trials<br />
Andrea Calabria, Luca Biasco, Fabrizio Benedicenti, Simone Leo,<br />
Martina Cesani, Gianluigi Zanetti, Elia Stupka, Alessandra Bifi,<br />
Alessandro Aiuti, Luigi Naldini, Eugenio Montini.<br />
518<br />
Mutually Dependent Barcode Strategy for Accurate<br />
Deep Sequencing <strong>of</strong> Vector Integration Sites<br />
Richard Gabriel, Cynthia C. Bartholomae, Frank Giordano, Raffaele<br />
Fronza, Stephanie Laufs, Christ<strong>of</strong> von Kalle, Manfred Schmidt.<br />
519<br />
Sequencing <strong>of</strong> a <strong>Gene</strong>tic Barcode Reveals Altered<br />
Population Dynamics in a Mouse Model <strong>of</strong> Transplanted<br />
Hematopoietic Stem <strong>Cell</strong>s Transduced with a Lentivirus<br />
Encoding LMO2<br />
Bryan E. Strauss, Daniela B. Zanatta, Rodrigo Aguiar, Maristela<br />
Tsujita, Primavera Borelli.<br />
520<br />
A New Strategy for Retroviral Vector Puriication Based<br />
on LNGR-Ab Immunomagnetic Selection<br />
Stornaiuolo Anna, Corna Stefano, Bossi Sergio, Bordignon Claudio,<br />
Rizzardi Gian Paolo, Bovolenta Chiara.<br />
521<br />
Lentiviral <strong>Gene</strong> <strong>Therapy</strong> in a SCID-X1 Mouse Model<br />
after Treatment with Granulocyte Colony Stimulating<br />
Factor<br />
Marshall W. Huston, Niek P. van Til, Rana Yadak, Yvette van<br />
Helsdingen, Gerard Wagemaker.<br />
522<br />
Development <strong>of</strong> Human Mesenchymal Stem <strong>Cell</strong>-Based<br />
Tumor-Homing Producer <strong>Cell</strong>s for Eficient Delivery <strong>of</strong><br />
Retroviral Replicating Vectors to Brain Tumors<br />
Shuichi Kamijima, Akihito Inagaki, Kei Hiraoka, Masamichi<br />
Takahashi, Quincy Tam, Emmanuelle Faure-Kumar, Janet Treger,<br />
Brooke Bogan, Christopher R. Logg, Noriyuki Kasahara.<br />
523<br />
Reducing In Vivo Clearance <strong>of</strong> Lentiviral Vectors by<br />
Immune <strong>Cell</strong>s in order To Improve Eficacy and Safety<br />
<strong>of</strong> <strong>Gene</strong> <strong>Therapy</strong><br />
Nisha G. Sosale, Irena I. Ivanovska, Richard K. Tsai, Philip K.<br />
Zoltick, Yale Goldman, Dennis E. Discher.<br />
524<br />
A Novel Retroviral Envelope as a Candidate for<br />
Pseudotyping Retroviral and Lentiviral Vectors<br />
Wenqin Xu, Jill Russ, Kristen Gorman, Kyle Delaney, Maribeth V.<br />
Eiden.<br />
Saturday, May 18, 2013<br />
<strong>Final</strong> <strong>Program</strong> SALT LAKE CITY, UTAH May 15–18, 2013<br />
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