Final Program - American Society of Gene & Cell Therapy
Final Program - American Society of Gene & Cell Therapy
Final Program - American Society of Gene & Cell Therapy
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Wednesday, May 15, 2013<br />
Abstract Directory, Wednesday, May 15, 2013<br />
Oral Abstract Session 135<br />
Chemical and Molecular Conjugates<br />
3:15 PM - 4:15 PM<br />
Room: 151 ABCG<br />
41 3:15 PM<br />
Optimized Polyplexes That Avoid Liver Uptake and<br />
Maintain Eficient <strong>Gene</strong> Transfer In Vivo<br />
Sanjib Khargharia, Koby Kizzire, Mark E. Ericson, Nick J.<br />
Baumhover, Kevin G. Rice.<br />
42 3:30 PM<br />
Synergistic Cancer <strong>Therapy</strong> by Simultaneous<br />
Expression and Silencing <strong>of</strong> Pro-Apoptotic and Pro-<br />
Survival <strong>Gene</strong>s Using Chimeric Nanoparticles<br />
Soo Kyung Cho, Jane Kim, Young Jik Kwon.<br />
43 3:45 PM<br />
Examining <strong>Cell</strong>-Penetrating Homochiral Cyclic Peptides<br />
as siRNA Non-Viral Transfection Agents<br />
Christiaan D. King, Ria L. Swanekamp, Bradley L. Nilsson, David A.<br />
Dean.<br />
44 4:00 PM<br />
Structure and Silencing Activity <strong>of</strong> Imidazole-<br />
Containing Peptide siRNA Polyplexes Are Dependent on<br />
Hydrogen Bonding<br />
Szu-Ting Chou, Kellie Hom, Lucas Tricoli, Jason Hustedt, Amy<br />
Lee, Joonil Seog, Jason Kahn, Qixin Leng, Daoning Zhang, Michael<br />
Shapiro, Archibald J. Mixson.<br />
Oral Abstract Session 136<br />
Infectious Diseases and Vaccines<br />
3:15 PM - 4:15 PM<br />
Room: 150 ABC<br />
45 3:15 PM<br />
Inducing Humoral and <strong>Cell</strong>ular Responses to Multiple<br />
Sporozoite and Liver-Stage Malaria Antigens Using<br />
pDNA<br />
Bernadette Ferraro, Kendra T. Talbot, Amritha Balakrishnan,<br />
Matthew P Morrow, Natalie A. Hutnick, Devin J. Myles, Devon J.<br />
Shedlock, Nyamekye Obeng-Adjei, Jian Yan, Rachel Shiver, Amir<br />
S. Khan, Maria Yang, Ami S. Brown, Ulrike Wille-Reece, Ashley<br />
Birkett, Niranjan Y. Sardesai, David B. Weiner.<br />
46 3:30 PM<br />
T-<strong>Cell</strong>s Edited To Express the C34 Peptide from gp41<br />
Heptad Repeat-2 Fused to CCR5 or CXCR4 Exhibit<br />
Robust Protection from Diverse HIV-1 Isolates<br />
Jianbin Wang, George J. Leslie, Jennifer Duong, Kevin L. Hua, Jenny<br />
J. Yan, Beth Haggarty, Andrea P. Jordon, Josephine Romano, Lei<br />
Zhang, Edward J. Rebar, Philip D. Gregory, James A. Hoxie, Michael<br />
C. Holmes.<br />
47 3:45 PM<br />
Integrase-Defective Lentiviral Vector-Induced Dendritic<br />
<strong>Cell</strong>s: Clinical Development and Validation <strong>of</strong> CD4+/<br />
CD8+ T <strong>Cell</strong> Responses for Combination with Adoptive<br />
CMV-Speciic T-<strong>Cell</strong> <strong>Therapy</strong><br />
Anusara Daenthanasanmak, Constanca Figueiredo, Eliana<br />
Ruggiero, Manfred Schmidt, Arnold Ganser, Renata Stripecke.<br />
48 4:00 PM<br />
Engineering Resistance to HIV-1 Infection with a Dual<br />
Therapeutic Lentiviral Vector<br />
Bryan P. Burke, Maureen P. Boyd, Michelle L. Millington, Helen<br />
Impey, Jane Zhang, Maria V. Carroll, Joanna Camba-Colon, Naomi<br />
Keech, Frederic Delebecque, Orit Wolstein, Annett Howe, Rachel<br />
Koldej, Tamara Nicolson, Bernard R. Levin, Valerie Rezek,<br />
Dimitrios N. Vatakis, Scott G. Kitchen, Louis R. Breton, Jeffrey S.<br />
Bartlett, Ge<strong>of</strong>f P. Symonds.<br />
Oral Abstract Session 137<br />
<strong>Cell</strong> Processing and Vector Production<br />
4:20 PM - 5:20 PM<br />
Room: 151 ABCG<br />
49 4:20 PM<br />
gc Cytokines IL7 and IL15 Expanded Chimeric Antigen<br />
Receptor-Redirected T <strong>Cell</strong>s (CAR-T) with Superior<br />
Antitumor Activity In Vivo<br />
Yang Xu, Ming Zhang, Aruna Mahendravada, Barbara Savoldo,<br />
Gianpietro Dotti.<br />
50 4:35 PM<br />
Large-Scale Clinical-Grade Retroviral Vector Production<br />
in iCELLis Nano Bioreactor<br />
Xiuyan Wang, Malgorzata Olzzewska, Jinrong Qu, Teresa<br />
Wasielewska, Shirley Bartido, Gregory Hermetet, Michel Sadelain,<br />
Isabelle Riviere.<br />
51 4:50 PM<br />
Large Scale Production <strong>of</strong> Lentiviral Vectors Using<br />
Serum Free Suspension <strong>Cell</strong> Culture System<br />
Amelia H. Thomas, Kevin Brown, Francis H. Pierciey, Jr, Gabor<br />
Veres, Byoung Y. Ryu.<br />
52 5:05 PM<br />
A Single Baculovirus for the Production <strong>of</strong> rAAV8 Viral<br />
Vectors<br />
Lionel Galibert, Aurélien Jacob, Bérangère Langlet-Bertin,<br />
Marjorie Boutin Fontaine, Delphine Bonnin, Christophe Lecomte,<br />
Christel Rivière, Otto W. Merten.<br />
90<br />
<strong>Final</strong> <strong>Program</strong> SALT LAKE CITY, UTAH May 15–18, 2013