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Final Program - American Society of Gene & Cell Therapy

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Abstract Directory, Saturday, May 18, 2013<br />

Saturday, May 18, 2013<br />

Poster Session III, continued<br />

3:45 PM - 5:45 PM<br />

Room: Exhibit Hall C/D<br />

Adenovirus and Other DNA Virus Vectors II<br />

556<br />

Enhanced Anti-Tumor Eficacy by Oncolytic Adenovirus<br />

Using a Stimuli Responsive Block Copolymer<br />

mPEG-b-Poly(His)<br />

Joung-Woo Choi, You Han Bae, Chae-Ok Yun.<br />

557<br />

Distinct Integration Proiles after Sleeping Beauty<br />

Transposase-Mediated Somatic Integration from AAV<br />

and Adenoviral Vectors<br />

Wenli Zhang, Christina Rauschhuber, Martin Haeusl, Nadine<br />

Muether, Anja Ehrhardt.<br />

558<br />

Screening and Characterization <strong>of</strong> Alternative<br />

Adenovirus Serotypes with Enhanced Virus-<br />

Lateralization Ability In Vitro for Improved Antitumor<br />

Eficacy<br />

Junji Uchino, David T. Curiel, Hideyo Ugai.<br />

559<br />

Improved Animal Models for Testing <strong>Gene</strong> or <strong>Cell</strong><br />

Therapies for Atherosclerosis<br />

Liang Du, Jingwan Zhang, David Dichek.<br />

560<br />

Liver Retargeting <strong>of</strong> Adenovirus Using Robo4 Promoter<br />

and Hexon Substitution<br />

Sergey A. Kaliberov, Lyudmila N. Kaliberova, Zhi Hong Lu,<br />

Meredith A. Preuss, Justin A. Barnes, Cecil R. Stockard, William E.<br />

Grizzle, Jeffrey M. Arbeit, David T. Curiel.<br />

561 (Moved to Poster Session I after Abstract 138)<br />

Lister Strain Vaccinia Virus Demonstrates Favourable<br />

Anti-Tumor Eficacy and Tumor-Selectivity Compared<br />

to Western Reserve Strain<br />

Jonathan Hughes, Pengju Wang, Ghassan Alusi, Vipul Bhakta,<br />

Yongchao Chu, Hailiang Shi, Iain McNeish, Andrea McCart, Istvan<br />

Fodor, Nicholas Lemoine, Yaohe Wang.<br />

562<br />

Development <strong>of</strong> a Novel Vaccine Vector Based on<br />

Synthesized Adenovirus Genome<br />

Yong Yang, Chao Zhang, Xiang Wang, Yudan Chi, Dongming Zhou.<br />

563<br />

Construction <strong>of</strong> a Novel Bicistronic Adenoviral Vector<br />

Feilong Jie, Shengyao Wang, Jie Luo, Na Zhang, Jingang Zhang,<br />

Hongwei Li.<br />

564<br />

Ciproloxacin Regulates Negatively Egr-1<br />

Transcriptional Activity in Human Primary Tenocytes<br />

Transduced with Ad-Egr-1/Luc<br />

Francisco Martinez-F, Araceli Barrera-Lopez, Hugo Sandoval-<br />

Zamora, Karina Guzman-M, Alejandro Jimenez-Orozco, Christian Y.<br />

Lomeli-R, David T. Curiel, Rebecca E. Franco-Bourland.<br />

DNA Vectorology & <strong>Gene</strong> Targeting II<br />

565<br />

A Placebo Controlled Phase IIb Clinical Study<strong>of</strong><br />

Tissue<strong>Gene</strong>-C (TG-C) in Patients with Osteoarthritis<br />

Jung Jong Cho, Tae Won Kim, Yeo Myeong Park, Eu <strong>Gene</strong> Jeong,<br />

Moon Jong Noh, Kwan Hee Lee, Bum Sup Lee.<br />

566<br />

A Novel Oncolytic HSV Design Based on the Common<br />

Over-Expression <strong>of</strong> miR-21 in Tumors<br />

Marco Marzulli, Lucia Mazzacurati, Bonnie Reinhart, Mark E.<br />

Hatley, Joseph C. Glorioso, Paola Grandi, Justus B. Cohen.<br />

567<br />

Comparing the Activity <strong>of</strong> TALENs Constructed with<br />

Different Guanine-Targeting RVDs<br />

Yanni Lin, Thomas J. Cradick, Eli J. Fine, Gang Bao.<br />

568<br />

In Vivo Cleavage <strong>of</strong> Transgene Donors Promotes<br />

Nuclease-Mediated Targeted Integration<br />

Sandra Cristea, Yevgeniy Freyvert, Yolanda Santiago, Michael C.<br />

Holmes, Fyodor D. Urnov, Philip D. Gregory, Gregory J. Cost.<br />

569<br />

Helper Independent Self-Inactivating Chimeric<br />

PiggyBac Transposases for Genomic Targeting in<br />

Human <strong>Cell</strong>s<br />

Jesse B. Owens, Johann Urschitz, Ilko Stoytchev, Stefan Moisyadi.<br />

570<br />

Eficacy with Extremely Low Doses <strong>of</strong> Plasmid DNA<br />

Using Small Molecule Targeted Delivery <strong>of</strong> Bilamellar<br />

Invaginated Vesicles (BIVs) to Melanoma Tumor<br />

Xenografts<br />

Nancy S. Templeton, Li Chen, Connor Phalon, Phillip B. Maples,<br />

Neil Senzer, John Nemunaitis.<br />

571<br />

Zinc Finger Nuclease-Based <strong>Gene</strong> <strong>Therapy</strong> for Arginase<br />

I Deiciency as a Model for Curing Single-Enzyme Urea<br />

Cycle Disorders<br />

Ragini Bhargava, Hana Park, Sarah Novic<strong>of</strong>f, Alok V. Joglekar,<br />

Donald B. Kohn, Gerald S. Lipshutz.<br />

572<br />

Poly(2-Dimethylaminoethyl Methacrylate)-<br />

Functionalized Graphene Oxide Nanolakes for Eficient<br />

siRNA Delivery<br />

Jung Eun Lee, Min Sang Lee, Jeong A. Nam, Nak Won Kim, Sung<br />

Young Park, Ji Hoon Jeong.<br />

130<br />

<strong>Final</strong> <strong>Program</strong> SALT LAKE CITY, UTAH May 15–18, 2013

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