Final Program - American Society of Gene & Cell Therapy
Final Program - American Society of Gene & Cell Therapy
Final Program - American Society of Gene & Cell Therapy
You also want an ePaper? Increase the reach of your titles
YUMPU automatically turns print PDFs into web optimized ePapers that Google loves.
Abstract Directory, Thursday, May 16, 2013<br />
Poster Session I, continued<br />
4:00 PM - 6:00 PM<br />
Room: Exhibit Hall C/D<br />
AAV Vectors I<br />
118<br />
Productive Life Cycle <strong>of</strong> the AAV2 in the Complete<br />
Absence <strong>of</strong> a Conventional Polyadenylation Signal<br />
Lina Wang, Yuan Wang, Yuan Lu, George V. Aslanidi, Arun<br />
Srivastava, Changquan Ling, Chen Ling.<br />
119<br />
A Unique Biological Property <strong>of</strong> an AAV9 Mutant<br />
Showing Increased <strong>Cell</strong> Attachment in the Presence and<br />
Absence <strong>of</strong> AAV5<br />
Kei Adachi, Alex Summers, Hiroyuki Nakai.<br />
120<br />
Effective Transduction <strong>of</strong> Common Marmoset with rAAV<br />
1 and 9 To <strong>Gene</strong>rate NHP Model <strong>of</strong> Muscular Dystrophy<br />
Hironori Okada, Hidetoshi Ishibashi, Hiromi Hayashita-Kinoh,<br />
Tomoko Chiyo, Yuko Nitahara-Kasahara, Takashi Okada, Shin’ichi<br />
Takeda.<br />
121<br />
Precise Evaluation <strong>of</strong> NAb Status Against Adeno-<br />
Associated Viral Vectors and an Approach toward<br />
Managing Its Inhibitory Effect<br />
Hiroaki Mizukami, Jun Mimuro, Shuji Hishikawa, Tomokazu<br />
Ikemoto, Ryosuke Uchibori, Tomonori Tsukahara, Masashi Urabe,<br />
Akihiro Kume, Asuka Sakata, Tsukasa Ohmori, Seiji Madoiwa,<br />
Yoichi Sakata, Keiya Ozawa.<br />
122<br />
Dissection <strong>of</strong> Key Parameters Inluencing Ex Vivo AAV<br />
Library Selections<br />
Eike Kienle, Dirk Grimm.<br />
123<br />
Peptide-Mediated Retargeting <strong>of</strong> 12 AAV Serotypes<br />
Anna Sacher, Kathleen Börner, Eike Kienle, Hans-Georg<br />
Kraeusslich, Martin Mueller, Dirk Grimm.<br />
124<br />
Creation <strong>of</strong> Liver-Detargeting AAV2-Derived Mutants<br />
Based on the Knowledge <strong>of</strong> AAV9 Capsid Functions<br />
Kei Adachi, Michael Verga, Hiroyuki Nakai.<br />
125<br />
Cruciform Hairpin Structure <strong>of</strong> AAV Genome Is<br />
Speciically Subject to ATM-Dependent Silencing <strong>of</strong><br />
<strong>Gene</strong> Expression<br />
Marcela P. Cataldi, Kim Zaraspe, Haiyan Fu, Douglas M. McCarty.<br />
Adenovirus and Other DNA Virus Vectors I<br />
126<br />
Shielding the Hexon Hyper Variable Region 1 <strong>of</strong><br />
Ad5-Based <strong>Gene</strong> Transfer Vectors by PEGylation<br />
Decreases Sequestration by Erythrocytes and Increases<br />
Blood Coagulation Factor XMediated Hepatocyte<br />
Transduction<br />
Lea Krutzke, Jan-Michael Prill, Tatjana Engler, Stefan Kochanek,<br />
Florian Kreppel.<br />
127<br />
Therapeutic Eficacy in a Breast Cancer Model <strong>of</strong> Novel<br />
Conditionally Replicative Adenovirus (CRAd) Based<br />
upon the Deletion <strong>of</strong> Minor Core Protein <strong>Gene</strong> V<br />
Hideyo Ugai, George C. Dobbins, Minghui Wang, David T. Curiel.<br />
128<br />
No Recombinant Vector Sequences Detected in<br />
Tumor Tissues from Two Research Subjects Received<br />
Adenovirus Ornithine Transcarbamylase <strong>Gene</strong> <strong>Therapy</strong><br />
Li Zhong, Shaoyong Li, Mengxin Li, Yu Zhang, Brendan Lee, Mark L.<br />
Batshaw, James M. Wilson, Guangping Gao.<br />
129<br />
Oncolytic Adenovirus Expressing IL-23 and p35<br />
Elicits IFN-g- and TNF-a-Co-Producing T <strong>Cell</strong>-Mediated<br />
Antitumor Immunity<br />
Il-Kyu Choi, Yan Li, Eonju Oh, Chae-Ok Yun.<br />
130<br />
Wnt Decoy Receptor (sLRP6E1E2) Induces Antiibrotic<br />
Effect Via Inhibition <strong>of</strong> Wnt Signaling in Keloid Scars<br />
Jung-Sun Lee, Won Jai Lee, Chae-Ok Yun.<br />
131<br />
Versican Stimulates Adenoviral Transgene Expression<br />
in a JAK Dependent Manner<br />
Patricia Y. Akinfenwa, Wesley S. Bond, Mary Y. Hurwitz, Richard L.<br />
Hurwitz.<br />
132<br />
Replication <strong>of</strong> Human Adenoviruses in Non-Human<br />
<strong>Cell</strong>s In Vitro and In Vivo<br />
Catherine M. Crosby, Mallory A. Turner, Michael A. Barry.<br />
133<br />
Adenovirus Serotypes Differ in Their Susceptibility to<br />
Neutralization by Mouse Serum: Role <strong>of</strong> Coagulation<br />
Factor X<br />
Jie Tian, Zhili Xu, Andrew P. Byrnes.<br />
134<br />
Non-Covalent Coating <strong>of</strong> Adenoviral Vectors with<br />
PAMAM Dendrimer Conjugates Allows for CAR<br />
Independent Virus Uptake and Targeting to the EGF<br />
Receptor<br />
Alexandra Vetter, Kulpreet S. Virdi, Sigrid Espenlaub, Wolfgang<br />
Rödl, Ernst Wagner, Florian Kreppel, Christine Spitzweg, Manfred<br />
Ogris.<br />
Thursday, May 16, 2013<br />
<strong>Final</strong> <strong>Program</strong> SALT LAKE CITY, UTAH May 15–18, 2013<br />
97
Change language