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E3 ligase TRIM72 negatively regulates myogenesis by IRS-1 ...

E3 ligase TRIM72 negatively regulates myogenesis by IRS-1 ...

E3 ligase TRIM72 negatively regulates myogenesis by IRS-1 ...

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<strong>TRIM72</strong> is highly expressed during C2C12 <strong>myogenesis</strong><br />

0 1 2 3 4<br />

<strong>TRIM72</strong><br />

0 1 2 3 4 5 6 7<br />

days after<br />

differentiation<br />

<strong>TRIM72</strong><br />

Cav-3<br />

Cav-3<br />

Myogenin<br />

Myogenin<br />

MyoD<br />

MHC<br />

MHC<br />

Actin<br />

Myostatin<br />

MyoD<br />

Myf5<br />

<strong>IRS</strong>-1<br />

Coomasie<br />

Staining<br />

Lee et al., CDD, 2010

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