E3 ligase TRIM72 negatively regulates myogenesis by IRS-1 ...

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UbcH2 mRNA and protein are increased during C2C12 myogenesis Differentiation days 0 1 2 3 4 5 UbcH2 UbcH3 UbcH5b UbcH6 UbcH2/GAPDH 4.0 3.0 2.0 1.0 ** * Real-time PCR UbcH7 UbcH8 UbcH10 Ubc12 0 1 2 3 4 5 Differentiation days Differentiation days 0 1 2 3 4 5 UBCH2 Ubc13 TRIM72 Cav-3 Mgn MyHC IRS1 MyoD Cav-3 GAPDH Actin
Molecular association of TRIM72 with UbcH2 IP:MBP IB:His IB:MBP IB:His Purified TRIM72 and E2 enzymes In vitro binding assay
Page 1 and 2: E3 ligase TRIM72 negatively regulat
Page 3 and 4: Insulin action through lipid rafts
Page 5 and 6: Functional proteomics of lipid raft
Page 7 and 8: C2C12 Myogenesis Myoblasts Myotubes
Page 9 and 10: TRIM72 gene analysis Myoblasts Myot
Page 11 and 12: TRIM72 is highly expressed during C
Page 13 and 14: What is a molecular target of TRIM7
Page 15 and 16: TRIM72 supresses IRS-1 phosphorylat
Page 17 and 18: TRIM72 negatively regulates myogene
Page 19 and 20: Ring Finger domain of TRIM72 Consen
Page 21 and 22: RING domain of TRIM72 is required f
Page 23 and 24: RING domain does not prevent bindin
Page 25 and 26: RING domain of TRIM72 is required f
Page 27 and 28: TRIM72 disruption enhances MyoD-dri
Page 29: E3 ligase activity Protein Ubiquit
Page 33 and 34: UbcH2 knockdown enhances myogenesis
Page 35 and 36: TRIM72 is highly expressed in soleu
Page 37 and 38: IRS-1 expression level is elevated
Page 39 and 40: E3 ligase TRIM72 negatively regulat
Page 41: Korea University Lab of Cell Signal

E3 ligase TRIM72 negatively regulates myogenesis by IRS-1 ...

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