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E3 ligase TRIM72 negatively regulates myogenesis by IRS-1 ...

E3 ligase TRIM72 negatively regulates myogenesis by IRS-1 ...

E3 ligase TRIM72 negatively regulates myogenesis by IRS-1 ...

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<strong>TRIM72</strong> inhibition of <strong>myogenesis</strong> is released <strong>by</strong> UbcH2 knockdown<br />

Si-control<br />

HA-<strong>TRIM72</strong><br />

Si-UbcH2<br />

HA-<strong>TRIM72</strong><br />

9<br />

8<br />

7<br />

6<br />

5<br />

4<br />

3<br />

2<br />

1<br />

si-control<br />

HA-<strong>TRIM72</strong><br />

si-Ubch2<br />

HA-<strong>TRIM72</strong><br />

The number of nucleus<br />

In HA-positive cells<br />

MyHC<br />

HA<br />

DAPI<br />

C2C12 myotubes

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