E3 ligase TRIM72 negatively regulates myogenesis by IRS-1 ...

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Skeletal muscle size is increased in TRIM72-disrupted mice. 15.0 *
IRS-1 expression level is elevated in TRIM-disrupted skeletal muscle WT - + KO - + Insulin 0 5 10 0 5 10 Insulin (min) TRIM72 pAkt Akt pERK Erk Actin TRIM72 IRS-1 pAkt Akt pERK ERK Actin C2C12 Myoblasts pY IRS-1 IP:IRS-1 Mouse soleus muscle
Page 1 and 2: E3 ligase TRIM72 negatively regulat
Page 3 and 4: Insulin action through lipid rafts
Page 5 and 6: Functional proteomics of lipid raft
Page 7 and 8: C2C12 Myogenesis Myoblasts Myotubes
Page 9 and 10: TRIM72 gene analysis Myoblasts Myot
Page 11 and 12: TRIM72 is highly expressed during C
Page 13 and 14: What is a molecular target of TRIM7
Page 15 and 16: TRIM72 supresses IRS-1 phosphorylat
Page 17 and 18: TRIM72 negatively regulates myogene
Page 19 and 20: Ring Finger domain of TRIM72 Consen
Page 21 and 22: RING domain of TRIM72 is required f
Page 23 and 24: RING domain does not prevent bindin
Page 25 and 26: RING domain of TRIM72 is required f
Page 27 and 28: TRIM72 disruption enhances MyoD-dri
Page 29 and 30: E3 ligase activity Protein Ubiquit
Page 31 and 32: Molecular association of TRIM72 wit
Page 33 and 34: UbcH2 knockdown enhances myogenesis
Page 35: TRIM72 is highly expressed in soleu
Page 39 and 40: E3 ligase TRIM72 negatively regulat
Page 41: Korea University Lab of Cell Signal

E3 ligase TRIM72 negatively regulates myogenesis by IRS-1 ...

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