MANUAL PHYSIOLOGY PRACTICAL - Repository:The Medical ...

FM/UOJ
Group A: Control – 1
They form a control group. The subjects will only collect urine, every 30
minutes for measurements.
Group B: Control – 2
This also is a control group. The subjects will collect urine as others and will
replace the fluid lost during the time by drinking water. 25 ml in excess of urinary
output. (25 ml is to replace water lost by insensible perspiration).
Group C: Frusemide
The subject will receive an injection of fursemide (Lasyx) 20 mg.
intramascularity after the first 30 minutes.
Group D: 1 L Water – 1 dose
The subject will drink one litre (1 L) of water after the first 30 minutes. They
must drink the water slowly and steadily in less than 15 minutes.
Group E: 1 L water – 5 doses
The subject will drink one litre (1L) of water in five installments; they will
drink 200 ml every 30 minutes.
Group F: 1 L Saline
The subjects will drink one litre (1L) of isotonic saline after the first 30
minutes. They must drink the saline slowly and steadily in less than 15 minutes. They
should be careful not to provoke vomitish feeling.
Group G: Dehydration
The subjects are different from the others in that they should have prepared
themselves 5 hours ahead in order to dehydrate themselves. On the previous day they
are identified and instructed to consume moderate amounts of fluids with breakfast
and to take nothing after 8 A.M. on the day of experiment.
Kidney
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