19.06.2015 Views

Lab Manual - eScience Labs

Lab Manual - eScience Labs

Lab Manual - eScience Labs

SHOW MORE
SHOW LESS

Create successful ePaper yourself

Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.

<strong>Lab</strong> 14: Mendelian Genecs<br />

Concepts to explore:<br />

• Gregor Mendel<br />

• Law of segregaon<br />

• Homozygous<br />

• Heterozygous<br />

• Independent assortment<br />

• Dominant vs. recessive<br />

• Incomplete dominance<br />

• Co-dominance<br />

• Genotype<br />

• Phenotype<br />

• Monohybrid cross<br />

• Dihybrid cross<br />

• Punne square<br />

Introducon<br />

In 1866, Gregor Mendel, an Austrian Monk, published a paper entled “Experiments in plant hybridiza-<br />

on”. It went largely unnoced unl 1900 when it was rediscovered and subsequently became the<br />

basis for what we now refer to as Mendelian Genecs.<br />

Mendel was the first to recognize:<br />

• Inherited characters are determined by specific factors (now recognized these as genes).<br />

• These factors occur in pairs (genes).<br />

When both alleles of a gene are the same they are said to be homozygous, while if they are different<br />

they are said to be heterozygous. When gametes form, these factors segregate so that each gamete<br />

contains only one allele for each gene. Remember, alleles reside on the chromosomes that are dividing.<br />

These original observaons lead to what we now refer to as The law of segregaon and the law of<br />

independent assortment.<br />

Figure 1: Law of Segregaon<br />

151

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!