CPG for Eating Disorders

In yet another RCT (Carter, 1998 261 ), the overall dropout rate was 12%. Dropouts pergroups were: GSH: 24%, SH: 0% and wait-list: 4%. No adverse effects were reported.RCT1+Recommendations(See recommendations 9.GP.12. to 9.GP.14.)9.5. Interpersonal Therapy (IPT)9.5.1. Anorexia nervosa9.5.1.1. What is the efficacy of IPT in patients with AN?The answer is based on a high-quality SRSE (1++) elaborated by the AHRQ of the US (2006) 31 .The results of the previous SRSE are maintained in a further high-quality (1++) SRSE based onthe same RCT published one year later (Bulik, et al., 2007) 202 . The updated search has notyielded any new RCTs.Scientific EvidenceIn an RCT (McInstosh, 2005; New Zealand) 216 CBT (N=19) was compared to IPT(N=21) and to non-specific supportive clinical management (NSCM) (N=16) in women(17-40 years) with AN and low weight who were treated on an outpatient basis over 20weeks. NSCM was superior to IPT in improving the general functioning of patients andin dietary restraint at 20 weeks of treatment; NSCM was superior to CBT in improvinggeneral functioning at 20 weeks, and CBT was superior to IPT in improving dietaryrestraint at 20 weeks.RCT1+Summary of the Evidence(See summary of the evidence for psychological treatment)Recommendations(See recommendations 9.GP.1. to 9.GP.11.)9.5.1.2. What is the safety of IPT in patients with AN?The answer is based on two high-quality SRSE (1++) described in the question regarding IPTefficacy 31, 202 .CLINICAL PRACTICE GUIDELINE FOR EATING DISORDERS117