CPG for Eating Disorders

Recommendations(See also recommendations 9.GP.12. to 9.GP.17.)B 9.5.3.1. IPT-BED can be offered to patients with persistent BED (adapted fromrecommendation 8.2.7.5. of the NICE CPG).9.5.3.2. What is the safety of interpersonal therapy in patients withBED?The evidence derives from the NICE CPG (2004) 30 and high-quality SRSE 31, 245 . The updatedsearch has not yielded any new evidence. Studies are briefly described in question 9.5.3.1.Scientific EvidenceThere is insufficient evidence to determine that there are significant differencesbetween CBT and IPT in the number of dropouts for any reason by the end of treatment(2 RCTs; N=198; Wilfley, 1993 235 and 2002 234 ; RR: 1.89; 95% CI: 0.89 to 4.02).RCT1 +In an RCT (Wilfley, 2002) 234 , dropout rate for CBT was 20% and 16% for IPT. Noadverse effects were reported.RCT1 +Summary of the Evidence(See summary of the evidence for psychological treatment)Recommendations(See recommendations 9.GP.12. to 9.GP.17.)9.6. Family Therapy (FT) (systemic or unspecified)9.6.1. Anorexia nervosa9.6.1.1. What is the efficacy of FT (systemic) in patients with AN?The answer is based on the NICE CPG (2004) 30 and on the high-quality SRSE (1++) elaboratedby the AHRQ of the US (2006) 31 and a more recently published SRSE (Bulik, et al., 2007) 202 . Theupdated search has not yielded any new evidence on FT.CLINICAL PRACTICE GUIDELINE FOR EATING DISORDERS122