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Beer : Health and Nutrition

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The Basics of Human <strong>Nutrition</strong> 93<br />

for thiamine if alcohol is present at high levels. It is equally important to stress that<br />

excessive intake of vitamins may have adverse effects. For the most part this pertains<br />

to two of the fat-soluble vitamins, A <strong>and</strong> D, though B 6 at levels above 50 mg per day or<br />

nicotinic acid in excess of 2–6 g per day are of concern for neurological damage <strong>and</strong><br />

liver damage respectively (Finglas 2003).<br />

Minerals<br />

Table 4.3 lists the requirements of the human for minerals <strong>and</strong> their various impacts.<br />

Minerals comprise only 4–6% of the body (Freel<strong>and</strong>-Graves & Trotter 2003) <strong>and</strong> some<br />

of them are needed only in vanishing quantities. Calcium, chloride, magnesium, phosphorus,<br />

potassium <strong>and</strong> sodium are the major minerals. Chromium, copper, uoride,<br />

iodide, iron, manganese, silicon <strong>and</strong> zinc are needed in trace quantities. Arsenic, boron,<br />

molybdenum, nickel, selenium <strong>and</strong> vanadium are ‘ultra trace’ minerals.<br />

Table 4.3 Minerals <strong>and</strong> their significance.<br />

Mineral Notes<br />

Calcium Needed for teeth <strong>and</strong> bones (e.g. lack causing osteoporosis in older women) <strong>and</strong> blood<br />

clotting. By interaction with phosphate these two minerals mutually antagonise one<br />

another’s uptake. Also binding with other components will limit uptake, e.g. oxalate<br />

Phosphorus Needed for teeth <strong>and</strong> bones <strong>and</strong> energy metabolism<br />

Magnesium Needed for nerve <strong>and</strong> muscle function<br />

Iron Component of haemoglobin <strong>and</strong> myoglobin. Uptake may be limited by complex<br />

formation, e.g. with phytate <strong>and</strong> phosphate<br />

Copper Component of key oxidative enzymes<br />

Cobalt Part of vitamin B 12<br />

Zinc Needed by several enzymes; implicated in reproduction, growth, skin integrity <strong>and</strong><br />

wound healing<br />

Sodium Maintenance of osmotic equilibrium <strong>and</strong> body uid volume<br />

Chloride Maintenance of osmotic equilibrium <strong>and</strong> body uid volume. Also needed in manufacture<br />

of stomach hydrochloric acid<br />

Potassium Helps sodium in regulating ionic balance across membranes<br />

Iodine Part of thyroid hormone, de ciency causing goitre<br />

Fluoride Needed for sound teeth <strong>and</strong> bones<br />

Chromium Glucose metabolism, insulin sensitivity<br />

Manganese Cartilage <strong>and</strong> bone equity, lipid <strong>and</strong> carbohydrate metabolism<br />

Silicon Bone calci cation <strong>and</strong> cartilage formation<br />

Arsenic Taurine <strong>and</strong> polyamine metabolism<br />

Selenium Antioxidant, thyroid hormone metabolism<br />

Boron Energy utilisation, bone development<br />

Molybdenum Sulphur <strong>and</strong> nucleic acid metabolism<br />

Nickel Production of hormones<br />

Vanadium Iodine metabolism

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