Annual Report of Activities CNC 2008 - Center for Neuroscience and ...

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Rosete Pais“Papilomavirus humano e cancro do colo do útero: estudo de factores imunológicos do hospedeiro quepodem condicionar o desenvolvimento de doença”.September 30, 2008Supervisor: Teresa C. MartinsRui Gonçalo Batista Mamede da Cruz“Aminopeptidase N de Arabidopsis thaliana: Expressão e Caracterização.”Supervisor: Paula VeríssimoSara DinizAnimal BiologyMay, 2008Supervisor: João Ramalho Santos120
Technology TransferTranslational research and technology transfer have been progressivly developed in CNC leading to apromising interaction with Industry and local authorities. The outcome of this interaction was theparticipation of CNC as a founding member of ABAP (Association envolving seven Municipal Councils ofthe Center Region of Portugal) aiming at knowledge based development). The main contribution of CNCfor that goal was the creation of technology transfer unit (Biocant) in colaboration with CantanhedeMunicipal Council.This unit became the anchor of Biocant Park a Biotechnology Park that is rapidly growing by atractingnew Biotechnology companies.1. BIOCANTBiocant is a private, non‐profit, innovation centrecreated by CNCB together with the municipality ofCantanhede for technology transfer in biotechnology.Founded 3 years ago, Biocant has grown to become areference in the field and the catalyst of Biocant Park,the first Portuguese biotechnology park.Biocant is organized into seven main functional unitswith highly qualified teams and state of art equipment:Genomics, Cellular Biology, Molecular Biotechnology,Microbiology, Bioinformatics, System Biology, TissueEngineering, and Advanced Services. Biocant providesservices and R&D activities based on post‐genomicplatforms such as whole‐genome sequencing, DNAchips, proteomics, interactomics and metabolomics.121Several research projects are currently in progress,some in collaboration with national or internationalresearch institutions, hospitals and companies.Throughout the past year Biocant has filed four patentapplications and its researchers published papers injournals such as PNAS and JBC. Biocant expects tospin‐out its first company by the end of 2008.2. Companies operating in Biocant ParkAt the present 8 companies operate in Biocant Park: Crioestaminal, GeneBox, GenePrediT, GeneLab,Novexem, Hematos, 4Health and Biocant Ventures. Along with Biocant they form a biotech cluster ofexcellence, bringing together over 100 researchers, in a unique enabling environment. Linking basic andapplied research more closely to successful innovation, Biocant paved the way for a new paradigm ofeconomic development in the Center Region of Portugal.
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General ObjectivesThe CNC major mis
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OrganizationThe Center for Neurosci
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Microbiology | Milton CostaMicrobio
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per year) will be proposed by the g
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Neuroprotection and Neurogenesis in
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Retinal Dysfunction and Neurogenesi
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Glutamatergic synapses | Head: Ana
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Neuronal Cell Death and Neuroprotec
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Molecular Mechanisms of Disease | H
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PublicationsAgasse F, Bernardino L,
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Santiago AR, Carvalho, CM, Carvalho
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“Nano‐transportadores de base l
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Vectors and Gene Therapy GroupM. Co
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Molecular Systems Biology | Head: A
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Vectors and Gene Therapy | Head: Ma
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PublicationsAlves S, Nascimento‐F
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Area C | Cell and Molecular Toxicol
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Mitochondrial Toxicology and Pharma
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Pharmacometrics GroupAmílcar Falc
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Free Radicals and Antioxidants in B
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Pharmacometrics | Head: Amílcar Fa
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Correia S, Carvalho C, Santos MS, P
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Area D | MicrobiologyCoordinator |
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Microbiology of Extreme Environment
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Medical Mycology - Yeast Research |
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Area E | Biophysics and Biomedical
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Inorganic Biochemistry and Molecula
Page 69 and 70: Inorganic Biochemistry and Molecula
Page 71 and 72: Cell Biophysics |Head: Luís Martin
Page 73: Sobral AJFN, Justino LLG, Santos AC
Page 76 and 77: Future PlansThere is an enormous we
Page 78 and 79: Paula MotaSara M. Diniz Martins Lop
Page 80 and 81: Biology of Reproduction and Human F
Page 82 and 83: Insulin Resistance and Adipocyte |
Page 85 and 86: Biomedical Inter‐Institutional Re
Page 87 and 88: 3. Pediatric Research: metabolic di
Page 89 and 90: PublicationsSantos MJ, Cleto S, Men
Page 91: 7. Research in brain cancer: geneti
Page 94 and 95: Grafting SVZ neural stem cell cultu
Page 96 and 97: Structure‐function analysis of th
Page 98 and 99: Anticancer Effects of of Phytochemi
Page 100 and 101: Investigaciones Biomédicas “Albe
Page 102 and 103: Participation in the organization o
Page 104 and 105: May 2008Member of the organizing co
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Page 108 and 109: Genome BiologyFebruary 25 ‐ 27Isa
Page 110 and 111: Seminars2008 Series | CNC Audithori
Page 112 and 113: 13.6.2008Cells caught in the act: M
Page 114 and 115: 5.12.2008Unexpected fate and functi
Page 116 and 117: Elisabete Ferreiro“Cross‐talk b
Page 118 and 119: Ana Isabel Vicente Rafael“Estudos
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Page 126 and 127: FLOW CYTOMETRY UNITHead of Unit: Is
Page 128 and 129: MASS SPECTROMETRY UNITHead of Unit:
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Page 132 and 133: Amino Acid AnalysisOur laboratory r
Page 134 and 135: 2. Areas of Expertise / Research /
Page 136 and 137: Multiple SclerosisAn extension of t
Page 138 and 139: 2.2. Centre for Bioavailability Stu
Page 140 and 141: StaffCoordinatorTice Macedo, MD, Ph
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Page 144 and 145: Compatible solutes from extremophil
Page 146 and 147: Proteases aspárticas secretadas em
Page 148 and 149: Mecanismos de plasticidade sinápti
Page 150 and 151: Clivagem dos transportadores vesicu
Page 152 and 153: ʺBIOINK ‐ Aprendizagem increment
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Page 156 and 157: Henrique Faneca (Auxiliar Inv., CNC
Page 158 and 159: Liliana Bernardino 100Luis Miguel E
Page 160 and 161: João Teixeira 100João Teodoro 100
Page 162 and 163: Patricia Henriques Domingues 100Pat
Page 164 and 165: ADMINISTRATIVE STAFFTime % at CNCAr
Page 166 and 167: Sandra Isabel M. Cardoso (Auxiliar
Page 168 and 169: Molecular Biotechnology and HealthE
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Cell and Molecular ToxicologyLeonor
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MicrobiologyMilton Costa, PhD, Coor
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Paulo Gameiro Guerreiro 100Pedro Co
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Marta Isabel Rodrigues Baptista 100
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Url: http://www.cnbc.pt | Email: in
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