PublicationsAgasse F, Bernardino L, Kristiansen H, Christiansen SH, Ferreira R, Silva B, Grade S, Woldbye DP <strong>and</strong>Malva JO (<strong>2008</strong>) Neuropeptide Y Promotes Neurogenesis in Murine Subventricular Zone. Stem Cells 26:1636‐1645.Agasse F, Bernardino L, Silva B, Ferreira R, Grade S <strong>and</strong> Malva JO (<strong>2008</strong>) Response to histamine allows thefunctional identification <strong>of</strong> neuronal progenitors, neurons, astrocytes <strong>and</strong> immature cells in subventricularzone cell cultures. Rejuvenation Res. 11:187‐200.Agostinho P, Lopes JP, Velez Z, Oliveira CR (<strong>2008</strong>) Overactivation <strong>of</strong> calcineurin induced by amyloid‐beta<strong>and</strong> prion proteins. Neurochem. Int. 52, 1226‐1233.Almeida S, Sarmento‐Ribeiro AB, Januário C, Rego AC, Oliveira CR (<strong>2008</strong>) Evidence <strong>of</strong> apoptosis <strong>and</strong>mitochondrial abnormalities in peripheral blood cells <strong>of</strong> Huntingtonʹs disease patients. Biochem. Biophys.Res. Commun. 374, 599‐603.Álvaro AR, Martins J, Costa AC, Fern<strong>and</strong>es E, Carvalho F, Ambrósio AF, Cavadas C (<strong>2008</strong>) Neuropeptide Yprotects retinal neural cells against cell death induced by ecstasy. <strong>Neuroscience</strong> 152:97‐105.Álvaro AR, Martins J, Araújo IM, Rosmaninho‐Salgado J, Ambrósio AF, Cavadas C (<strong>2008</strong>) Neuropeptide Ystimulates retinal neural cell proliferation – involvement <strong>of</strong> nitric oxide. J Neurochem 105:2501‐2510.Araújo IM, Gil J, Carreira BP, Mohapel P, Petersén Å, Pinheiro PS, Soulet D, Bahr BA, Brundin P, CarvalhoCM (<strong>2008</strong>) Calpain activation is involved in early caspase‐independent neurodegeneration in thehippocampus following status epilepticus. J. Neurochem. 105:666‐676.Arduíno D, Silva D, Cardoso SM, Chaves S, Oliveira CR, Santos MA (<strong>2008</strong>) Synthesis <strong>and</strong> investigation <strong>of</strong>new hydroxypyridinone based iron‐chelators as potential anti‐neurodegenerative drug c<strong>and</strong>idates. Front.Biosci. 13,6763‐6774.Bernardino L, Agasse F, Silva B, Ferreira R, Grade S <strong>and</strong> Malva JO (<strong>2008</strong>) Tumor necrosis factor‐alphamodulates survival, proliferation, <strong>and</strong> neuronal differentiation in neonatal subventricular zone cellcultures. Stem Cells 26: 2361‐2371.28Bernardino L, Balosso S, Ravizza T, Marchi N, Ku G, R<strong>and</strong>le JC, Malva JO <strong>and</strong> Vezzani A (<strong>2008</strong>)Inflammatory events in hippocampal slice cultures prime neuronal susceptibility to excitotoxic injury: acrucial role <strong>of</strong> P2X(7) receptor‐mediated IL‐1beta release. J. Neurochem. 106: 271‐280.Canas PM, Duarte JM, Rodrigues RJ, Köfalvi A, Cunha RA (<strong>2008</strong>) Modification upon aging <strong>of</strong> the density<strong>of</strong> presynaptic modulation systems in the hippocampus. Neurobiol. Aging 25. [Cardoso S, Santos RX, Carvalho C, Correia S, Pereira GC, Pereira SS, Oliveira PJ, Santos MS, Proença T,Moreira PI (<strong>2008</strong>) Doxorubicin increases the susceptibility <strong>of</strong> brain mitochondria to Ca2+‐inducedpermeability transition <strong>and</strong> oxidative damage. Free Radic. Biol. Med. 45, 1395‐1402.Carvalho AL, Caldeira MV, Santos SD, Duarte CB. (<strong>2008</strong>) Role <strong>of</strong> the brain‐derived neurotrophic factor atglutamatergic synapses. Br. J. Pharmacol. 153 Suppl 1:S310‐24.Correia S, Carvalho C, Santos MS, Proença T, Nunes E, Duarte AI, Monteiro P, Seiça R, Oliveira CR,Moreira PI (<strong>2008</strong>) Met<strong>for</strong>min protects the brain against the oxidative imbalance promoted by type 2diabetes. Med. Chem. 4:358‐364.Cunha GM, Canas PM, Melo CS, Hockemeyer J, Müller CE, Oliveira CR, Cunha RA (<strong>2008</strong>) Adenosine A2Areceptor blockade prevents memory dysfunction caused by beta‐amyloid peptides but not by scopolamineor MK‐801. Exp. Neurol. 210:776‐81.Cunha‐Oliveira T, Rego AC, Oliveira CR (<strong>2008</strong>) Cellular <strong>and</strong> molecular mechanisms involved in theneurotoxicity <strong>of</strong> opioid <strong>and</strong> psychostimulant drugs. Brain Res Rev. 58:192‐208.Cunha RA, Ferré S, Vaugeois JM, Chen JF (<strong>2008</strong>) Potential therapeutic interest <strong>of</strong> adenosine A2A receptorsin psychiatric disorders. Curr. Pharm. Des. 14:1512‐24.
Domingues AF, Arduíno DM, Esteves ARF, Swerdlow RH, Oliveira CR, Cardoso SM (<strong>2008</strong>) Mitochondria<strong>and</strong> Ubiquitin Proteasomal System interplay in Parkinsonʹs disease. Free Radic. Biol. Med. 45:820‐825.Domingues AF, Esteves ARF, Swerdlow RH, Oliveira CR, Cardoso SM (<strong>2008</strong>) Calpain‐mediated MPP+toxicity in mitochondrial DNA depleted cells. Neurotox. Res. 13,31‐88.Donato R, Rodrigues RJ, Takahashi M, Tsai MC, Soto D, Miyagi K, VillafuertesRG, Cunha RA, EdwardsFA. (<strong>2008</strong>) GABA release by basket cells onto Purkinje cells, in rat cerebellar slices, is directly controlled bypresynaptic purinergic receptors, modulating Ca2+ influx. Cell Calcium. 44:521‐32.Duarte AI, Santos P, Oliveira CR, Santos MS, Rego AC (<strong>2008</strong>) Insulin neuroprotection against oxidativestress is mediated by Akt <strong>and</strong> GSK‐3β signaling pathways <strong>and</strong> changes in protein expression. BiochemBiophys Acta – Mol Cell Res 1783: 994‐1002.Esteves ARF, Arduíno DM, Swerdlow RH, Oliveira CR, Cardoso SM (<strong>2008</strong>) Oxidative Stress potentiatesalpha‐synuclein oligomerization in PD Cybrids. Antiox. Redox Signal.Esteves ARF, Domingues AF, Ferreira IL, Januário C, Swerdlow RH, Oliveira CR <strong>and</strong> Cardoso SM (<strong>2008</strong>)Mitochondrial dysfunction occurs in parkinson’s disease cybrids containing an nt2 neuron‐like nuclearbackground. Mitochondrion 8,219‐228.Ferreiro E, Costa R, Marques S, Cardoso SM, Oliveira CR, Pereira C (<strong>2008</strong>) Involvement <strong>of</strong> mitochondria inendoplasmic reticulum stress‐induced apoptotic cell death pathway triggered by the prion peptidePrP106‐126. J. Neurochem. 104,766‐776.Ferreiro E, Oliveira CR, Pereira CM (<strong>2008</strong>) The release <strong>of</strong> calcium from the endoplasmic reticulum induced byamyloid‐beta <strong>and</strong> prion peptides activates the mitochondrial apoptotic pathway. Neurobiol. Dis. 30,331‐342.Figueiredo C, Pais TF, Gomes JR, Chatterjee S (<strong>2008</strong>) Neuron‐microglia crosstalk up‐regulates neuronal FGF‐2 expression which mediates neuroprotection against excitotoxicity via JNK1/2. J. Neurochem. 107, 73‐85.Gil JM, Rego AC (<strong>2008</strong>) Mechanisms <strong>of</strong> neurodegeneration in Huntington’s disease. Eur. J. Neurosci. 27,2803‐2820.Gomes AR, Ferreira JS, Paternain AV, Lerma J, Duarte CB, Carvalho AL (<strong>2008</strong>) Characterization <strong>of</strong>alternatively spliced is<strong>of</strong>orms <strong>of</strong> AMPA receptor subunits encoding truncated receptors. Mol. Cell Neurosci.37, 323–334.29Gonçalves J, Martins T, Ferreira R, Milhazes N, Borges F, Ribeiro CF, Malva JO, Macedo TR <strong>and</strong> Silva AP(<strong>2008</strong>) Methamphetamine‐induced early increase <strong>of</strong> IL‐6 <strong>and</strong> TNF‐alpha mRNA expression in the mousebrain. Ann. N. Y. Acad. Sci. 1139:103‐111.Leal E, Aveleira CA, Castilho AF, Baptista FI, Ambrósio AF (<strong>2008</strong>) Muller cells do not influence leukocyteadhesion to retinal endothelial cells. Ocul. Immunol. Inflamm. 16:173‐179.Matos M, Augusto E, Oliveira CR, Agostinho P (<strong>2008</strong>) Amyloid‐beta peptide decreases glutamate uptake incultured astrocytes: involvement <strong>of</strong> oxidative stress <strong>and</strong> MAP Kinase cascades. <strong>Neuroscience</strong> 156,898‐910.Rebola N, Lujan R, Cunha RA, Mulle C (<strong>2008</strong>) Adenosine A2A receptors are essential <strong>for</strong> long‐termpotentiation <strong>of</strong> NMDA‐EPSCs at hippocampal mossy fiber synapses. Neuron 57:121‐34.Resende R, Ferreiro E, Pereira C, Oliveira CR (<strong>2008</strong>) ER stress is involved in Aβ‐induced GSK‐3β activation<strong>and</strong> tau phosphorylation. J. Neurosci. Res. 86,2091‐2099.Resende R, Ferreiro E, Pereira C, Oliveira CR (<strong>2008</strong>) Neurotoxic effect <strong>of</strong> oligomeric <strong>and</strong> fibrillar species <strong>of</strong>Aβ1‐42 peptide. Involvement <strong>of</strong> ER calcium release in oligomers‐induced cell death. <strong>Neuroscience</strong> 155,725‐737.Resende R, Moreira PI, Proença T, Deshp<strong>and</strong>e A, Busciglio J, Pereira C, Oliveira CR (<strong>2008</strong>) Brain oxidativestress in a triple‐transgenic mouse model <strong>of</strong> Alzheimer disease. Free Radic. Biol. Med. 44,2051‐2057.Rodrigues RJ, Canas PM, Lopes LV, Oliveira CR, Cunha RA (<strong>2008</strong>) Modification <strong>of</strong> adenosine modulation<strong>of</strong> acetylcholine release in the hippocampus <strong>of</strong> aged rats. Neurobiol. Aging 29:1597‐601Saavedra A, Baltazar G, Duarte EP (<strong>2008</strong>) Driving GDNF expression: The green <strong>and</strong> the red traffic lights.Prog. Neurobiol. 86, 186‐215.
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