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Annual Report of Activities CNC 2008 - Center for Neuroscience and ...

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InternationalizationInternationalization has been a permanent concern <strong>of</strong> the <strong>CNC</strong> strategy. To attain this goal the researchershave been encouraged to establish colaborations <strong>and</strong> joint projects with laboratories abroad, <strong>and</strong> tocolaborate in the organizaton <strong>of</strong> international scientific meetings. A third action line <strong>of</strong> theInternationalization strategy is the Graduate Studies Programme which is described in the next section <strong>of</strong>this report.Projects jointly with laboratories abroad<strong>Neuroscience</strong> <strong>and</strong> DiseaseAdenosine A2A <strong>and</strong> dopamine D4‐7 receptor heteromers: molecular target <strong>for</strong> caffeine in attention‐deficithyperactivity disorder. Francisco Ciruela (University <strong>of</strong> Barcelona, Spain), Cristina Oliveira (Hospitais daUniversidade de Coimbra, Portugal), Francisco Corte‐Real (Instituto de Medicina Legal, Portugal),Rodrigo Cunha (<strong>CNC</strong>, Portugal).Axonal transport <strong>of</strong> mitochondria in the triple transgenic mouse model <strong>of</strong> Alzheimer disease. J. Busciglio(Univ. Cali<strong>for</strong>nia, USA), Claudia Pereira (<strong>CNC</strong>, Portugal).Cell cycle reactivation in the triple transgenic mouse model <strong>of</strong> Alzheimer disease. S. Oddo / F. LaFerla(Univ. Cali<strong>for</strong>nia, USA), Rui Costa , Claudia Pereira (<strong>CNC</strong>, Portugal).93Characterization <strong>of</strong> the BDNF‐induced changes in the proteome <strong>of</strong> cultured hippocampal neurons.Michael Fountoulakis (Foundation <strong>for</strong> Biomedical Research <strong>of</strong> the Academy <strong>of</strong> Athens, Greece), Carlos B.Duarte (<strong>CNC</strong>, Portugal).Does enhanced adenosine <strong>for</strong>mation prevent the early memory dysfunction <strong>and</strong> synaptotoxicitycharacteristic <strong>of</strong> Alzheimer’s disease? Detlev Boison (R.S. Dow Neurobiology Laboratories, USA), RodrigoCunha (<strong>CNC</strong>, Portugal).Dysfunctional mitochondria recruits oligomeric <strong>and</strong> fibrillar β‐syn to shut them down. R. Swerdlow (Univ.Virginia Health System, USA), Claudia Pereira (<strong>CNC</strong>, Portugal).Effect <strong>of</strong> purines in the developing hippocampus: consequences <strong>for</strong> the establishment <strong>of</strong> circuits related tolearning <strong>and</strong> memory. Christophe Bérnard (Institut de Neurobiologie de la Méditerranée, France), ScottRivkees (Yale University, USA), Rodrigo Cunha (<strong>CNC</strong>, Portugal).Effect <strong>of</strong> the Contactin/Caspr complex on AMPA receptor‐mediated excitatory postsynaptic currents inhippocampal neurons in culture. Christophe Mulle (University <strong>of</strong> Bordeaux, Bordeaux, France), Ana LuisaCarvalho (<strong>CNC</strong>, Portugal).Endocannabinoids <strong>and</strong> neurogenesis in the subventricular zone. Pr<strong>of</strong>. Giovanni Marsicano (InstituteFrançois Magendie, Bordeaux, France), Ana P. Silva, Sara Xapelli, João O. Malva (<strong>CNC</strong>, Portugal).Endothelial ‐ neural stem cells crosstalk in stem cell niches: implications in brain tumor development. Pr<strong>of</strong>.Florence H<strong>of</strong>fmann (University <strong>of</strong> South Cali<strong>for</strong>nia, Los Angeles), Fabienne Agasse, S<strong>of</strong>ia Grade,Alex<strong>and</strong>ra Rosa (<strong>CNC</strong>, Portugal).

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