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Annual Report of Activities CNC 2008 - Center for Neuroscience and ...

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PublicationsAlves S, Nascimento‐Ferreira I, Auregan G, Hassig R, Dufour N, Brouillet E, Pedroso de Lima MC,Hantraye P, Déglon N*, Pereira de Almeida* L. (<strong>2008</strong>) Allele‐specific RNA silencing <strong>of</strong> mutant ataxin‐3mediates neuroprotection in a rat model <strong>of</strong> Machado‐Joseph disease. *Equal Contribution. PLoS ONE Oct8;3(10):e3341.Alves S, Régulier E, Nascimento‐Ferreira I, Hassig R, Dufour N, Koeppen A, Carvalho AL, Simões S,Pedroso de Lima MC, Brouillet E, Colomer Gould V, Déglon N, Pereira de Almeida L (<strong>2008</strong>) Striatal <strong>and</strong>nigral pathology in a lentiviral rat model <strong>of</strong> Machado‐Joseph disease. Hum. Mol. Genet. 17: 2071‐2083.Camacho R, Alves A, Silva CG <strong>and</strong> Brito RMM (<strong>2008</strong>) On Mining Protein Unfoling Simulation Data withInductive Logic Programming. Proceedings <strong>of</strong> the 2nd International Workshop on Practical Applications<strong>of</strong> Computational Biology <strong>and</strong> Bioin<strong>for</strong>matics (IWPACBB <strong>2008</strong>). Advances in S<strong>of</strong>t Computing 49, 175‐179.(ISBN 978‐3‐540‐85860‐7)Cardoso ALC, Simões S, Almeida LP, Plesnila N, Lima MCP, Wagner E <strong>and</strong> Culmsee C (<strong>2008</strong>) Tflipoplexes<strong>for</strong> neuronal siRNA delivery in vitro <strong>and</strong> in vivo: A promising system to mediate gene silencingin the CNS. J. Control. Release 132, 113–123.Monteiro CJP, Pereira MM, Pinto SMA, Simões AVC, Sá GFF, Arnaut LG, Formosinho SJ, Simões S <strong>and</strong>Wyatt MF (<strong>2008</strong>) Synthesis <strong>of</strong> amphiphilic sulfonamide halogenated porphyrins: MALDI‐TOFMScharacterization <strong>and</strong> evaluation <strong>of</strong> 1‐octanol/water partition coefficients. Tetrahedron 64(22), 5132‐5138.Fern<strong>and</strong>es E, Jorge AM, Silva CG, <strong>and</strong> Brito RMM (<strong>2008</strong>). A Knowledge Discovery Method <strong>for</strong> theCharacterization <strong>of</strong> Protein Unfolding Processes. Proceedings <strong>of</strong> the 2nd International Workshop onPractical Applications <strong>of</strong> Computational Biology <strong>and</strong> Bioin<strong>for</strong>matics (IWPACBB <strong>2008</strong>). Advances in S<strong>of</strong>tComputing 49, 180‐188. (ISBN 978‐3‐540‐85860‐7)Faneca H, Faustino A <strong>and</strong> Lima MCP (<strong>2008</strong>) Synergistic antitumoral effect <strong>of</strong> non‐viral HSV‐Tk/GCV genetherapy <strong>and</strong> vinblastine in mammary adenocarcinoma cells. J. Control. Release 126, 175‐184.Ferreira L*, Karp JM, Nobre L, Langer R* (<strong>2008</strong>) New opportunities: The use <strong>of</strong> nanotechnologies tomanipulate <strong>and</strong> track stem cells. Cell Stem Cell 3, 136‐146. *Corresponding authors.40Ferreira L, Squier T, Park H, Choe H, Kohane DS, Langer R (<strong>2008</strong>) Human embryoid bodies containingnano‐ <strong>and</strong> micro‐particulate delivery vehicles. Advanced Materials 20, 2285‐2291.Fuller J, Zugates G, Ferreira L, Ow H, Nguyen N, Wiesner U, Langer R (<strong>2008</strong>) Intracellular delivery <strong>of</strong>core‐shell fluorescent silica nanoparticles”. Biomaterials 29, 1526‐ 1532.Mahdavi A*, Ferreira L*, Sundback C, Nichol JW, Chan EP, Carter JD,Bettinger C, Patanavanich S,Chignozha L, Ben‐Joseph E, Galakatos A, Pryor H, Pomerantseva I, Masiakos P, Faquin W, Zumbuehl A,Hong S, Borenstein J, Vacanti J, Langer R, Karp JM (<strong>2008</strong>) A biodegradable <strong>and</strong> biocompatible Geckoinspiredtissue adhesiveʺ. Proceedings <strong>of</strong> the National Academy <strong>of</strong> Sciences 105(7), 2307‐2312. *Authorscontributed equally.Moreira JN, Santos A, Moura V, Lima MCP, Simões S (<strong>2008</strong>) Non‐viral lipid‐based nanoparticles towardscancer systemic gene silencing. Journal <strong>of</strong> Nanoscience <strong>and</strong> Nanotechnology May; 8:2187–2204.Nobre RJ, Almeida LP, Martins TC. (<strong>2008</strong>) Complete genotyping <strong>of</strong> mucosal human papillomavirus usinga restriction fragment length polymorphism analysis <strong>and</strong> an original typing algorithm. J. Clin Virol.May;42(1):13‐21. Epub <strong>2008</strong> Mar 4.Nunes‐Correia I, Rodríguez JM, Eulálio A, Carvalho AL, Citovsky V, Simões S, Faro C, Salas ML, Pedrosode Lima MC. African swine fever virus p10 protein exhibits nuclear import capacity <strong>and</strong> accumulates inthe nucleus during viral infection.Vet Microbiol. <strong>2008</strong> Jul 27;130(1‐2):47‐59.Penacho N, Filipe A, Simões S <strong>and</strong> Lima MCP (<strong>2008</strong>) Transferrin‐associated lipoplexes as gene deliverysystems: relevance <strong>of</strong> mode <strong>of</strong> preparation <strong>and</strong> biophysical properties. J. Membrane Biology 221, 141‐152.

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