STRATEGIC PLAN - ASPE - U.S. Department of Health and Human ...

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CHAPTER 5: Scientific Research and DevelopmentPerformance IndicatorsMost Recent ResultFY 2012 TargetStrategic Objective 4.1Strengthen the pool of qualified health and behavioral science researchers.4.1.1Through the National ResearchService Award program,increase the probabilitythat scientists continueparticipation in NIH-fundedresearch within the followingten years:a) Post-doctoral fellows; andb) Pre-doctoral trainees andfellows.Strategic Objective 4.2a) 13 percentage points; andb) 13 percentage points.a) 12+ percentage points; andb) 12+ percentage points.Increase basic scientific knowledge to improve human health and human development.4.2.1Develop and apply clinicallyone new imaging technique toenable tracking the mobility ofstem cells within cardiovasculartissues.Researchers in the NIHintramural program havedeveloped probes that arecompatible with opticalmicroscopy techniquesdeveloped by intramuralscientists.Develop one new imagingtechnique that is able to beclinically applied.4.2.2Identify at least one clinicalintervention that will delaythe progression or onset ofAlzheimer’s disease (AD), orprevent it.Nearly 1,000 new late-onset ADfamilies have been identifiedand recruited to the ADGenetics Initiative.Identify the next generation ofcompounds for testing in pilotclinical trials.4.2.3Develop a novel advancedpattern recognition algorithmto analyze data obtained fromimaging technologies to aidclinicians in diagnosing theearliest stage of disease, e.g.,brain cancer.The prototype patternrecognition algorithm hasbeen designed and trained torecognize anomalies in thepilot study of brain MagneticResonance SpectroscopicImaging (MRS) scans.Apply, in conjunction witha Cooperative Research andDevelopment Agreement(CRADA) partner, a patternrecognition algorithm toidentify early biomarkersof brain disease to otherdisease endpoints in clinicalapplications such as thoseused to identify breast cancermarkers.128 HHS Strategic Plan FY 2007-2012
CHAPTER 5: Scientific Research and DevelopmentMost Recent ResultFY 2012 TargetStrategic Objective 4.3Conduct and oversee applied research to improve health and well-being.4.3.1Conduct clinical trials to assessthe efficacy of at least three newtreatment strategies to reducecardiovascular morbidity/mortality in patients with type 2diabetes and/or chronic kidneydisease.Initial findings made public atthe annual American DiabetesAssociation meeting in June2006.Complete clinical trials andmake results available.Strategic Objective 4.4Communicate and transfer research results into clinical, public health, and human service practice.4.4.1Increase the number of AoAsupportedcommunity-basedsites that use evidencebaseddisease and disabilityprevention programs.27 sites 136 sites4.4.2Reduce the disparity betweenAfrican-Americans infants andWhite infants in back sleepingby 50% to reduce the risk ofSudden Infant Death Syndrome(SIDS).The SIDS rate for African-American infants is two timesgreater than that of Whiteinfants.Reduce disparity by 50%4.4.3Reduce the financialcost (or burden) of uppergastrointestinal (GI) hospitaladmissions by implementingknown research findings.$93.46 per U.S. resident ages 65to 85.10% reductionNote: Additional information about performance indicators is included in Appendix B.HHS Strategic Plan FY 2007-2012129
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U.S. DEPARTMENT OF HEALTH & HUMAN S
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Appendix h: endnotesXXX.CDC. (2005)
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