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Anaesthetists Handbook - MEDICAL EDUCATION at University ...

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Miscellaneous issuesincreasing the flow r<strong>at</strong>e will not increase the delivered oxygenconcentr<strong>at</strong>ion. The non-rebre<strong>at</strong>he masks can be used to delivergre<strong>at</strong>er than 60% oxygen with flow r<strong>at</strong>es of 10 – 15 L min -1 .Should you require a p<strong>at</strong>ient to have supplemental oxygenadministered, you must prescribe it on the drug chart. Oxygen maynot be administered if not prescribed. You should prescribe theappropri<strong>at</strong>e oxygen percentage. Altern<strong>at</strong>ively, prescribe nasalcannulas with a flow r<strong>at</strong>e (usually 2 L min -1 ).Paracetamol loading dosesParacetamol is an effective perioper<strong>at</strong>ive analgesic agent. Wherepracticable oral administr<strong>at</strong>ion is preferred – the intravenousprepar<strong>at</strong>ion is many times more expensive and the total costpressure of using intravenous paracetamol is high. Ward nurses willgive oral premedicants if you prescribe them, especially if you tell thenurses th<strong>at</strong> you have prescribed premedicants.The following st<strong>at</strong>ement was agreed <strong>at</strong> the anaesthesia departmentmeeting in January 2009 and <strong>at</strong> the trust’s Drugs and TherapeuticsCommittee in December 2009:“Paracetamol is an effective and safe analgesic widely used inperioper<strong>at</strong>ive care. Where indic<strong>at</strong>ed for prophylaxis or tre<strong>at</strong>ment ofsurgical pain, prescriptions for oral administr<strong>at</strong>ion can consist of aloading dose (where the p<strong>at</strong>ient is not consuming regularparacetamol) followed by regular dosing or tre<strong>at</strong>ment as required bythe p<strong>at</strong>ient. An appropri<strong>at</strong>e oral loading dose is a single dose of30 mg kg -1 or less, usually to a maximum dose of 2 g. This will lead tothe following dose recommend<strong>at</strong>ions:P<strong>at</strong>ient 70 kg or over. 2 g Leading to 5 g in the first 24 hours.P<strong>at</strong>ient under 70 kgbut over 50 kg.1.5 g Leading to 4.5 g in the first 24hours.“As with all prescriptions, the responsibility for adapting it to unusualcircumstances lies with the prescriber.”220 <strong>Anaesthetists</strong> <strong>Handbook</strong> January 2010

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