computer modeling in molecular biology.pdf

2 Modellinn Protein Structures 21the core was counted, and the root-mean-square deviation of the main chain atomsof the core was calculated. (The points corresponding to 100% residue identity areproteins for which the structure was determined in two or more crystal environments,and the deviations show that crystal packing forces can modify slightly the conformationof the proteins.) Figure 2-6 shows the changes in the fraction of residues in'? 2.4-c0cm>2m:3c 1.2-mc2 0 0.6-80.0 1I I I I 100 80 60 40 20 0Percent residue identityFigure 2-5. The relationship between the divergence of the amino-acid sequence of the coreof related proteins and the divergence of the main chain conformation of the core.c%o I 80 ' 60 I 40 I 2bSequence identity ("YO)' 0 'Figure 2-6. The relationship between the divergence of the amino-acid sequence of the coreof related proteins and the relative size of the core.