in Albania - Instituti i Shendetit Publik

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ALBANIAN MEDICAL JOURNAL SUPPLEMENTAssessment of iron status in Albanian children andwomen through biochemical iron indicatorsEhadu Mersini 1 , Genc Burazeri 2,31World Health Organization, Tirana Office, Tirana, Albania;2Institute of Public Health, Tirana, Albania;3Faculty of Public Health, University of Medicine, Tirana, Albania.Aim: To assess the iron status among Albanianchildren aged 6 months to 14 years and women 15-49 years in a cross-sectional study conducted in theprefectures of Shkodër, Kukës and periurban areasof Tirana.Methods: A total of 443 children 6-59 months, 530children 5-14 years, and 418 women 15-49 yearswere included in this study. Iron status was definedutilizing biochemical indicators. Iron depletion wasdefined as low serum ferritin (SF28 nmol/l) plus irondepletion. Iron deficiency anemia (IDA) was definedas ID with hemoglobin (Hb) below the WHOcutoff value for age and sex: 11.0 g/dl for children6-59 months, 11.5 gr/dl for children 5-11 years old,12.0g/ dl for children 12-14 years old and(nonpregnant) women 15-49 years old. Individualswith indication of inflammation (CRP>10mg/ l)were excluded from the analyses.Results: The prevalence of iron depletion amongchildren 6-59 months, children 5-14 years andwomen 15-49 years were 28.4%, 10.9% and 23.6%,respectively. The overall prevalence of ID and IDAamong children 6-59 months was: 9.1% and 7.5%,respectively; among children 5-14 years: 6.1% and3.4%, respectively; and among women 15-49 years:8.1% and 7.1%, respectively.Conclusion: Findings of this study indicate thatspecific attention should be given in Albania to ensurethat the dietary intake of iron is adequate forchildren, adolescent girls and women throughimplementation of integrated strategies that includeimprovement of dietary intake through education,food fortification and use of iron supplements.Keywords: anemia, deficiency, dietaryintake, irondepletion.108 ALBANIAN MEDICAL JOURNAL SUPPLEMENT
INTERNATIONAL PUBLIC HEALTH CONFERENCE IN TIRANA, ALBANIASignificance of HPV tests in women with cervicalsmears exhibiting squamous cells of uncertainsignificance (ASCUS)Anila Xhani 1 , Kozeta Filipi 21Maternity Geraldina Queen , Tirana, Albania;2Institute of Public Health, Tirana, Albania.Aim: In Albania, cervical cancer cases are diagnosedin advanced stages. The aim of our study was toassess the relationship between the humanpapillomavirus (HPV) tests and the cytologicalfindings.Methods: Overall, 1321 women participating in theopportunistic cytological screening in the Maternityof Tirana, Albania and 52 showing atypicalsquamous cells of uncertain significance (ASCUS)in their cervical smears were identified during theyear 2012. All women were invited for a repeatedexamination about three months later. At thatoccasion, a smear sample was collected and usedfor cytological examination and a concomitant HPVtest. HPV detection and typing were carried out bypolymerase chain reaction and HPVdeoxyribonucleoside acid (DNA) sequence analysis.Results: Women with an ASCUS diagnosis showeda normal cytology and a negative HPV test in 13.5%of the cases, abnormal cytologyand a positive HPVtest in 48% of the cases; in 21% of the women,the HPV test was positive, whereas cytology wasnormal; and in 17% of the women, the HPV testwas negative, whereas cytology was abnormal(ASCUS or more). HPV test was positive in 70%of ASCUS cases. HPV high-risk was detected in28% of HPV test positive and in 100% of casesdiagnosed in CIN 3. Oncogenic types detected were33, 16, 18, 52, 68, 51, 31, and 56.Conclusion: Our findings indicate that HPV testsidentify a larger group of women at risk to developcervical cancer in comparison with cytologicalexamination. As the HPV tests have a highersensitivity than the cytological screening, it issuggested that a HPV test in conjunction with adiagnosis of ASCUS can be employed moreefficiently to selected women for whom furtherfollow-up is recommended.Keywords: cervical cancer, HPV , smear.ALBANIAN MEDICAL JOURNAL SUPPLEMENT109
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