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in Albania - Instituti i Shendetit Publik

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INTERNATIONAL PUBLIC HEALTH CONFERENCE IN TIRANA, ALBANIAStress Reduction <strong>in</strong> the Secondary Prevention ofCardiovascular Disease Randomized, ControlledTrial of Transcendental Meditation and HealthEducation <strong>in</strong> Black <strong>in</strong>dividualsRobert H. Schneider 11Institute for Natural Medic<strong>in</strong>e and Prevention, Maharishi University of Management, Fairfield, USA.Context: Blacks have disproportionately high ratesof cardiovascular disease. Psychosocial stress maycontribute to this disparity. Previous trials on stressreduction with the Transcendental Meditation (TM)program have reported improvements <strong>in</strong> cardiovasculardisease risk factors, surrogate end po<strong>in</strong>ts,and mortality <strong>in</strong> blacks and other populations.Methods: This was a randomized, controlled trialof 201 black men and women with coronary heartdisease who were randomized to the TM programor health education. The primary end po<strong>in</strong>t was thecomposite of all-cause mortality, myocardial<strong>in</strong>farction, or stroke. Secondary end po<strong>in</strong>ts <strong>in</strong>cludedthe composite of cardiovascular mortality, revascularizations,and cardiovascular hospitalizations; bloodpressure; psychosocial stress factors; and lifestylebehaviors.Results: Dur<strong>in</strong>g an average follow-up of 5.4 years,there was a 48% risk reduction <strong>in</strong> the primary endpo<strong>in</strong>t <strong>in</strong> the TM group (hazard ratio, 0.52; 95%confidence <strong>in</strong>terval, 0.29 0.92; P=0.025). The TMgroup also showed a 24% risk reduction <strong>in</strong> thesecondary end po<strong>in</strong>t (hazard ratio, 0.76; 95%confidence <strong>in</strong>terval, 0.51 0.1.13; P=0.17). Therewere reductions of 4.9 mm Hg <strong>in</strong> systolic bloodpressure (95% confidence <strong>in</strong>terval -8.3 to 1.5 mmHg; P=0.01) and anger expression (P

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