in Albania - Instituti i Shendetit Publik
in Albania - Instituti i Shendetit Publik
in Albania - Instituti i Shendetit Publik
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ALBANIAN MEDICAL JOURNAL SUPPLEMENTType 2 diabetes mellitus and the geneticcomponent: opportunities for early preventionHerion Muja 11Faculty of Public Health, University of Medic<strong>in</strong>e, Tirana, <strong>Albania</strong>.Aim: Type 2 diabetes mellitus (DM) is reported tohave a genetic component. Changes <strong>in</strong> life-stylecharacteristics of <strong>Albania</strong>n population po<strong>in</strong>t towardan <strong>in</strong>creas<strong>in</strong>g prevalence of DM <strong>in</strong> the future. Anypreventive option could help to alleviate DMburden. Our aim was to determ<strong>in</strong>e the associationof family history of diabetes with the presence ofDM among <strong>Albania</strong>n adults.Methods: Dur<strong>in</strong>g April-November 2012, 845randomly selected urban Tirana <strong>in</strong>dividuals agede 18 years old were <strong>in</strong>terviewed. Participants wereasked to report if they had ever been diagnosedwith diabetes by a doctor or other medical staff andwhether they had any diabetic close relatives. B<strong>in</strong>arylogistic regression was used to assess the associationof family history with type 2 DM.Results: Mean age of participants was 50.4 yearsold (51.3 years <strong>in</strong> men and 49.7% <strong>in</strong> women). Theoverall prevalence of diabetes <strong>in</strong> this sample ofadults was 11.5% (no significant sex difference).Almost one third of respondents (32.4%) had atleast one close relative with diabetes. The likelihoodof hav<strong>in</strong>g DM was 4.6 time higher among thosewith a positive family history for diabetes comparedto those hav<strong>in</strong>g no diabetic relatives (OR=4.6, 95%CI:2.7-7.9) after multivariable adjustment analysis.Conclusion: Type 2 DM has a strong geneticcomponent among <strong>Albania</strong>n adult population.Educat<strong>in</strong>g the general population about this aspectcould raise the awareness of diabetic <strong>in</strong>dividualsclose relatives to regularly monitor their blood sugarlevels and avoid diabetes risk factors.Keywords: adults, diabetes mellitus, diabetes familyhistory.24 ALBANIAN MEDICAL JOURNAL SUPPLEMENT