Interventions for Tuberculosis Control and Elimination 2002

Cases per 1,000
140
120
100
80
60
40
20
0
TBN +
BCG -
TBN -
BCG -
Tuberculosis
cases
TBN -
BCG +
and bacteriologic investigations demonstrated conclusively that batches containing
both BCG and M. tuberculosis in varying proportions had been fed
to the infants during the epidemic. 676,678,681,682 Among the 53 fatal cases
ascertained by mid-July 1930, the interval between vaccination and death
ranged from 34 to 129 days with a median of 79 days.
100
Tuberculosis deaths
TBN +
BCG - TBN -
BCG -
TBN -
BCG +
Figure 55. Results from a non-randomized, self-selection evaluation of the effect
of BCG vaccination on tuberculosis cases and deaths among student nurses in
Norway. 670
Number of cases
30
20
10
0
Healthy
TB
TB death
February March April June
Weekly vaccinations with critical strain
Figure 56. Curve of the tuberculosis epidemic following an accidental mix of BCG
vaccine strain with a virulent strain of Mycobacterium tuberculosis in Lübeck,
Germany, 1930. 676