Interventions for Tuberculosis Control and Elimination 2002

prophylactic treatment of special populations). Where this has been achieved
and maintained over a substantial period of time, a reduction of the prevalence
of tuberculous infection by preventive chemotherapy must be considered
as the next logical step. Vaccination with BCG will supplement
tuberculosis control efforts, particularly in high-burden countries, mainly by
reducing disability and death in young children.
In this monograph, the approach chosen to discuss the various interventions
follows the sequence in the epidemiological model presented
elsewhere (figure 2). 1,9 Interventions aim at reducing the impact of
those risk factors recognized to promote the progression from one step
to the next in the chain of events in the pathogenesis of tuberculosis
(figure 3). 10
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Figure 3. Model of interventions based on the epidemiology of tuberculosis.
Reproduced from 10 by the permission of the publisher Marcel Dekker.