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Annual Scientific Report 2015

EMBL_EBI_ASR_2015_DigitalEdition

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Protein Data Bank in Europe<br />

Gerard Kleywegt and Sameer Velankar<br />

• Curated a record 4007 PDB entries;<br />

• Curated 452 EMDB entries;<br />

• Released 22 new EMPIAR entries;<br />

• In collaboration with partners in the US and Japan,<br />

extended the wwPDB deposition and annotation software,<br />

as well as the wwPDB structure-validation pipelines, to fully<br />

support 3DEM and NMR data;<br />

• Further developed EMPIAR, a rapidly growing public<br />

archive for raw 3DEM and tomography image data;<br />

• Released the fully redesigned PDBe website (including the<br />

PDB and EMDB entry pages), a powerful new search system<br />

and an API;<br />

• Improved and extended the internal production process and<br />

data and database infrastructure to support the new website,<br />

search system and API;<br />

• Intensified outreach and training efforts, ranging from<br />

social media to expert workshops.<br />

PDB entry 1TN2: A transfer RNA (tRNA) molecule<br />

structure determined by Aaron Klug. Aaron Klug developed<br />

crystallographic electron microscopy methods and<br />

elucidated the structure of tRNA, the nucleosome and the<br />

zinc-finger DNA-binding domain. For his work on these<br />

biologically important nucleic acid-protein complexes he<br />

received the 1982 Nobel Prize in Chemistry.<br />

<strong>2015</strong> EMBL-EBI <strong>Annual</strong> <strong>Scientific</strong> <strong>Report</strong> 21

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